1292268-13-3 Usage
Description
BocNH-PEG7-OH, also known as N-Boc-PEG7-alcohol, is a PEG (polyethylene glycol) linker that features a hydroxyl group and a Boc-protected amino group. This molecule is designed to enhance solubility in aqueous environments due to the hydrophilic nature of the PEG spacer. The presence of the hydroxyl group allows for additional derivatization or substitution with other reactive functional groups, while the Boc group can be removed under mild acidic conditions to reveal the free amine, making it a versatile building block in various chemical and pharmaceutical applications.
Uses
Used in Pharmaceutical and Chemical Industries:
BocNH-PEG7-OH is used as a versatile intermediate for the synthesis of various pharmaceutical and chemical compounds. The Boc-protected amino group provides a stable and easily modifiable handle for attaching other molecules or functional groups, facilitating the development of new drugs and chemical entities.
Used in Drug Delivery Systems:
In the field of drug delivery, BocNH-PEG7-OH is used as a component in the design of targeted drug delivery systems. The PEG spacer enhances the solubility and biocompatibility of the delivery vehicle, while the Boc-protected amine can be used to attach drug molecules or targeting ligands, allowing for the development of more effective and specific therapies.
Used in Bioconjugation:
BocNH-PEG7-OH is utilized as a bioconjugation agent to link biologically active molecules, such as peptides, proteins, or nucleic acids, to other molecules or surfaces. The hydroxyl group can be used to attach these biomolecules, while the Boc-protected amine ensures that the conjugation process does not interfere with the biological activity of the attached molecules.
Used in Surface Modification:
In the context of surface modification, BocNH-PEG7-OH is used as a coating agent to modify the properties of various surfaces, such as implants or sensors. The PEG spacer provides a hydrophilic and non-fouling surface, while the Boc-protected amine can be used to attach additional functional groups or biomolecules, tailoring the surface properties for specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1292268-13-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,9,2,2,6 and 8 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1292268-13:
(9*1)+(8*2)+(7*9)+(6*2)+(5*2)+(4*6)+(3*8)+(2*1)+(1*3)=163
163 % 10 = 3
So 1292268-13-3 is a valid CAS Registry Number.
1292268-13-3Relevant articles and documents
Modular synthesis of bifunctional linkers for materials science
Moreau, Julie,Marchand-Brynaert, Jacqueline
, p. 1641 - 1644 (2011/05/03)
A practical synthesis of α,ω-bifunctional linkers is described that is based on three building blocks, namely, thioctic acid, a spacer-arm of seven ethylene glycol units, and a functional motif dedicated to the selective immobilization of purposely tagged proteins. Such representative motifs are biotin, haloacetamide, maleimide, and nitrilotriacetic acid derivatives. The building blocks are connected through alkyl, amide, and/or carbamate linkages. Copyright
