1292281-78-7Relevant articles and documents
Structure based design and syntheses of amino-1H-pyrazole amide derivatives as selective Raf kinase inhibitors in melanoma cells
Kim, Mi-Hyun,Kim, Minjung,Yu, Hana,Kim, Hwan,Yoo, Kyung Ho,Sim, Taebo,Hah, Jung-Mi
, p. 1915 - 1923 (2011/05/05)
The synthesis of a novel series of N-(5-amino-1-(4-methoxybenzyl)-1H- pyrazol-4-yl amide derivatives 6a-o, 7a-s and their antiproliferative activities against A375P melanoma cell line were described. Most compounds showed competitive antiproliferative act