1292292-52-4

Basic information

• Product Name: C₅₂H₈₄NO₈⁽¹⁺⁾*I^(1-)
• CAS NO: 1292292-52-4
• Molecular Weight: 978.145
• Mol File: 1292292-52-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₅₂H₈₄NO₈⁽¹⁺⁾*I^(1-)(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₂H₈₄NO₈⁽¹⁺⁾*I^(1-)(1292292-52-4)
• EPA Substance Registry System: C₅₂H₈₄NO₈⁽¹⁺⁾*I^(1-)(1292292-52-4)

Safety Data

• Hazardous Substances Data: 1292292-52-4(Hazardous Substances Data)

Upstream product

• 104-57-4 benzyl formate 
• 505-54-4 thapsic acid 
• 146004-98-0 16-(benzyloxy)-16-oxohexadecanoic acid 
• 1292292-57-9 C₅₁H₈₁NO₈ 
• 74-88-4 methyl iodide 

Relevant articles and documents

Synthesis, characterization, and in vitro transfection activity of charge-reversal amphiphiles for DNA delivery

A series of charge-reversal lipids were synthesized that possess varying chain lengths and end functionalities. These lipids were designed to bind and then release DNA based on a change in electrostatic interaction with DNA. Specifically, a cleavable ester linkage is located at the ends of the hydrocarbon chains. The DNA release from the amphiphile was tuned by altering the length and position of the ester linkage in the hydrophobic chains of the lipids through the preparation of five new amphiphiles. The amphiphiles and corresponding lipoplexes were characterized by DSC, TEM, and X-ray, as well as evaluated for DNA binding and DNA transfection. For one specific charge-reversal lipid, stable lipoplexes of approximately 550 nm were formed, and with this amphiphile, effective in vitro DNA transfection activities was observed.