1293965-62-4

Basic information

• Product Name: 2-((1-methyl-1-phenylpent-4-en-2-yl)sulfanyl)-5-(4-methoxyphenyl)-4-methylthiazole N-oxide
• Synonyms: 2-((1-methyl-1-phenylpent-4-en-2-yl)sulfanyl)-5-(4-methoxyphenyl)-4-methylthiazole N-oxide
• CAS NO: 1293965-62-4
• Molecular Weight: 411.589
• Mol File: 1293965-62-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-((1-methyl-1-phenylpent-4-en-2-yl)sulfanyl)-5-(4-methoxyphenyl)-4-methylthiazole N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((1-methyl-1-phenylpent-4-en-2-yl)sulfanyl)-5-(4-methoxyphenyl)-4-methylthiazole N-oxide(1293965-62-4)
• EPA Substance Registry System: 2-((1-methyl-1-phenylpent-4-en-2-yl)sulfanyl)-5-(4-methoxyphenyl)-4-methylthiazole N-oxide(1293965-62-4)

Safety Data

• Hazardous Substances Data: 1293965-62-4(Hazardous Substances Data)

Upstream product

• 85924-68-1 2-phenylhex-5-en-2-ol 
• 529477-58-5 N-(hydroxy)-5-(p-methoxyphenyl)-4-methylthiazole-2(3H)-thione 
• 1293965-65-7 3-(1-methyl-1-phenylpent-4-en-1-oxy)-5-(4-methoxyphenyl)-4-methylthiazole-2(3H)-thione 

Relevant articles and documents

Tertiary alkoxyl radicals from 3-alkoxythiazole-2(3H)-thiones

This study deals with the synthesis of tert-O-alkyl thiohydroxamates and their use as tert-alkoxyl radical precursors. tert-Alkoxyl radicals were applied in mechanistic studies to determine rate constants of (i) p-chlorocumyloxyl radical addition to bicyclo[2.2.1]heptene (k=1×107 M -1 s-1), (ii) 2-phenylhex-5-en-2-oxyl radical 5-exo-trig-cyclization (kcis=3×109 s-1, ktrans=1×109 s-1), and (iii) 2-methyl-5-phenylpent-2-oxyl to 2-hydroxy-2-methyl-5-phenylpent-5-yl radical isomerization (1,5-H-atom shift; k=0.4-1.5×108 s-1). The reactions pose key steps in synthesis of 2,2,5-substituted tetrahydrofurans and 2-bromo-3-alkoxybicyclo[2.2.1]heptanes. Stereoselectivity in 5-exo-trig cyclization (2,5-cis) and intermolecular addition (exo/endo>99:1), originates from torsional strain in transition structures of alkoxyl radical reactions.