1293988-24-5

Basic information

• Product Name: 3-[3-(cyclohexylamino)-propoxy]-6-hydroxyxanthone
• Synonyms: 3-[3-(cyclohexylamino)-propoxy]-6-hydroxyxanthone
• CAS NO: 1293988-24-5
• Molecular Weight: 367.445
• Mol File: 1293988-24-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[3-(cyclohexylamino)-propoxy]-6-hydroxyxanthone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[3-(cyclohexylamino)-propoxy]-6-hydroxyxanthone(1293988-24-5)
• EPA Substance Registry System: 3-[3-(cyclohexylamino)-propoxy]-6-hydroxyxanthone(1293988-24-5)

Safety Data

• Hazardous Substances Data: 1293988-24-5(Hazardous Substances Data)

Upstream product

• 4142-51-2 (2-hydroxy-4-methoxyphenyl) (2',4'-dimethoxyphenyl)methanone 
• 15007-07-5 3,6-dimethoxy-9H-xanthen-9-one 
• 39828-35-8 2,4-dimethoxybenzoyl chloride 
• 91-52-1 2,4 dimethoxybenzoic acid 
• 1214-24-0 3,6-dihydroxy-xanthen-9-one 
• 108-91-8 cyclohexylamine 

Relevant articles and documents

Antioxidant xanthone derivatives induce cell cycle arrest and apoptosis and enhance cell death induced by cisplatin in NTUB1 cells associated with ROS

In an effort to develop novel antioxidant as anticancer agents, a series of xanthones were prepared. In vitro screening, the synthetic xanthones revealed significant inhibitory effects on xanthine oxidase and ABTS radical-cation scavenging activity. The selective compounds 2 and 8 induced an accumulation of NTUB1 cells in the G1 phase arrest and cellular apoptosis by the increase of ROS level. The combination of cisplatin and 2 significantly enhanced the cell death in NTUB1 cells. Compounds 2 and 8 did not show cytotoxic activity in selected concentrations against SV-HUC1 cells. The present results suggested that antioxidants 2 and 8 may be used as anticancer agent for enhancing the therapeutic efficacy of anticancer agents and to reduce their side effect.