129439-65-2Relevant articles and documents
A TOTAL SYNTHESIS OF (+)-GEODIAMOLIDES A AND B, THE NOVEL CYCLODEPSIPEPTIDES
Hirai, Yoshiro,Yakota, Katsuyuki,Yamazaki, Takao,Momose, Takefumi
, p. 1101 - 1119 (2007/10/02)
Diastereo-controlled total synthesis of (+)-geodiamolides A (1) and B (2) has been accomplished via a prior synthesis of the tetrapropionate-derived fragment 7 and of the halogenated N-methyltyrosyltripeptide 6, the latter involving direct halogenation of the tripeptide 5, and subsequent coupling of both fragments followed by the trichlorobenzoyl chloride-mediated macrolactonization, respectively.