129449-09-8 Usage
Description
Amino-PEG10-alcohol is a highly water-soluble polyethylene glycol (PEG) reagent characterized by its amine and hydroxyl functional groups. These groups provide reactivity with various compounds, such as carboxylic acids, activated N-hydroxysuccinimide (NHS) esters, and carbonyls (ketone, aldehyde), making it a versatile molecule for chemical modifications and conjugations.
Uses
Used in Pharmaceutical Industry:
Amino-PEG10-alcohol is used as a solubilizing agent for enhancing the water solubility of hydrophobic drugs, thereby improving their bioavailability and pharmacokinetic properties.
Used in Drug Delivery Systems:
Amino-PEG10-alcohol is used as a component in the design and synthesis of drug delivery systems, such as nanoparticles, liposomes, and hydrogels, due to its biocompatible and hydrophilic nature. It can also be used for targeting and controlled release of therapeutic agents.
Used in Chemical Synthesis:
Amino-PEG10-alcohol is used as a building block or intermediate in the synthesis of various PEGylated compounds, including PEGylated proteins, peptides, and small molecules, for a range of applications in biotechnology and pharmaceuticals.
Used in Diagnostics:
Amino-PEG10-alcohol is used as a modifier to enhance the stability and solubility of diagnostic agents, such as contrast agents for imaging techniques like magnetic resonance imaging (MRI) and computed tomography (CT).
Used in Material Science:
Amino-PEG10-alcohol is used as a component in the development of biocompatible and hydrophilic materials, such as coatings, surfaces, and scaffolds for tissue engineering and regenerative medicine applications.
Used in Cosmetics:
Amino-PEG10-alcohol is used as an ingredient in the formulation of cosmetics and personal care products, where it serves as a humectant, emollient, and solubilizing agent for various active ingredients.
Check Digit Verification of cas no
The CAS Registry Mumber 129449-09-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,4,4 and 9 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 129449-09:
(8*1)+(7*2)+(6*9)+(5*4)+(4*4)+(3*9)+(2*0)+(1*9)=148
148 % 10 = 8
So 129449-09-8 is a valid CAS Registry Number.
129449-09-8Relevant articles and documents
PROTAC compound for targeted degradation of IDO1, and preparation method and application thereof
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Paragraph 0024-0026; 0046-0048; 0051, (2020/06/17)
The invention provides a PROTAC compound represented by formula I and used for targeted degradation of IDO1, and a pharmaceutically acceptable salt, a hydrate or a solvate thereof. In the formula I, Xrepresents -CH2 or -C = O, Y represents -CH2 or -C= O, and n is a natural number from 2 to 9. The PROTAC compound for targeted degradation of the IDO1 has efficient activity of targeted degradation of the IDO1 protein.
GALACTOSE DERIVATIVE, DRUG CARRIER AND MEDICINAL COMPOSITION
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Page/Page column 23, (2010/11/27)
The object of the invention is to provide a novel and useful galactose derivative constituting a drug carrier by which a medicine can be efficiently transferred into the liver, a drug carrier comprising the derivative, and a pharmaceutical composition comprising the carrier and a medicine. The present invention relates to a galactose derivative made up of galactose, a suitable spacer and a certain lipid, a drug carrier comprising the derivative and a cationic lipid, and a pharmaceutical composition comprising the carrier and a medicine (preferably a double strand RNA, a double strand DNA, an oligo nucleic acid) .
