129467-08-9Relevant articles and documents
Synthesis of a photoaffinity-labeled (11Z)-retinal: Identification of retinal/rhodopsin cross-linked sites along the visual-transduction path
Souto, Maria L.,Um, Joann,Borhan, Babak,Nakanishi, Koji
, p. 2617 - 2628 (2007/10/03)
The retinal chromophore (11Z)-3-diazo-4-oxoretinal (1) with two photo-labile moieties has been synthesized by semi-hydrogenation of an 11-yne precursor with activated Zn in aqueous media. Incorporation of 1 into opsin yielded diazoketo rhodopsin (DK-Rh),
Photoaffinity labeling studies of bacteriorhodopsin with [ 15-3H]-3-diazo-4-keto-all-trans-retinal
Boehm, Marcus F.,Gawinowicz, Mary Ann,Foucault, Alain,Derguini, Fadila,Nakanishi, Koji
, p. 7779 - 7782 (2007/10/02)
Photoaffinity mapping can be used to help clarify the tertiary structures of the retinal proteins bacteriorhodopsin (bR) and rhodopsin (Rh). An efficient photoaffinity labeled retinal analogue, [l5-3H]-all-trans-3-diazo-4-ketoretinal (specific