129505-09-5

Basic information

• Product Name: (2R,2'R)-N-<2'-(hydroxyamino)-3'-phenylpropanoyl>bornane-10,2-sultam
• CAS NO: 129505-09-5
• Molecular Weight: 378.492
• Mol File: 129505-09-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R,2'R)-N-<2'-(hydroxyamino)-3'-phenylpropanoyl>bornane-10,2-sultam(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,2'R)-N-<2'-(hydroxyamino)-3'-phenylpropanoyl>bornane-10,2-sultam(129505-09-5)
• EPA Substance Registry System: (2R,2'R)-N-<2'-(hydroxyamino)-3'-phenylpropanoyl>bornane-10,2-sultam(129505-09-5)

Safety Data

• Hazardous Substances Data: 129505-09-5(Hazardous Substances Data)

Upstream product

• 94594-90-8 (2R)-bornane-10,2-sultam 
• 645-45-4 hydrocinnamic acid chloride 
• 127392-81-8 1-((3aS,6R,7aR)-8,8-dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)-3-phenylpropan-1-one 

Downstream Products

• 673-06-3 D-(R)-phenylalanine 
• 105806-89-1 (2R)-N-isobutylphenylalanine 
• 105806-84-6 (2R)-N-ethylphenylalanine 
• 129568-84-9 (2R,2'R)-N-(2'-amino-3'-phenylpropanoyl)bornane-10,2-sultam 
• 35016-65-0 (2R)-(N-hydroxy)phenylalanine 

Relevant articles and documents

Asymmetric Synthesis of α-Amino Acids and α-N-Hydroxyamino Acids from N-Acylbornane-10,2-sultams: 1-Chloro-1-nitrosocyclohexane as a Practical +> Equivalent

Successive treatment of N-acylsultams 3 with sodium hexamethyldisilazide, 1-chloro-1-nitrosocyclohexane (1), and aq.HCl gave diastereoisomerically pure, crystalline N-hydroxyamino-acid derivatives 5.These were converted into various amino acids 7, N-hydroxyamino acids 8, and an N-Boc-amino acid 9. (S,S)-Isoleucine (17) and (S,S)-2-acetamido-3-phenylbutyric acid (23) were obtained from N-crotonoylsultam 15 via 1,4-addition of an organomagnesium or organocopper reagent followed by enolate 'amination' with 1.