1295471-72-5

Basic information

• Product Name: C₁₈H₂₃N₅O₆
• Synonyms: C₁₈H₂₃N₅O₆
• CAS NO: 1295471-72-5
• Molecular Weight: 405.411
• Mol File: 1295471-72-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₃N₅O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₃N₅O₆(1295471-72-5)
• EPA Substance Registry System: C₁₈H₂₃N₅O₆(1295471-72-5)

Safety Data

• Hazardous Substances Data: 1295471-72-5(Hazardous Substances Data)

Upstream product

• 23754-55-4 pactamycate 
• 1295471-18-9 C₃₃H₃₈N₄O₅Si 
• 1295471-17-8 C₃₂H₃₄N₄O₅Si 
• 1295471-54-3 C₃₂H₃₆N₄O₅Si 
• 1295471-16-7 C₃₈H₅₀N₄O₅Si₂ 
• 1295471-14-5 C₃₈H₅₁NO₆Si₂ 
• 1295471-10-1 C₃₈H₄₉NO₆Si₂ 
• 1295471-06-5 C₃₈H₄₉NO₅Si₂ 
• 1295471-04-3 C₃₈H₅₁NO₆Si₂ 
• 1295471-53-2 C₃₈H₅₁NO₆Si₂ 
• 1295471-03-2 C₃₉H₅₃NO₅Si₂ 
• 1403757-82-3 (4S,5R,6R,7S,8S,9S)-8-(3-acetylphenylamino)-9-azido-7-((tert-butyldiphenylsilyloxy)methyl)-6,7-dihydroxy-1-(4-methoxybenzyl)-4,6-dimethyl-3-oxa-1-azaspiro[4.4]nonan-2-one 
• 1295471-35-0 C₃₄H₄₁N₅O₆Si 
• 1295471-70-3 C₃₅H₄₃N₅O₅Si 

Downstream Products

• 23754-55-4 pactamycate 
• 1295471-36-1 C₂₆H₂₉N₅O₈ 
• 1295471-30-5 C₂₀H₃₀N₆O₆ 
• 1073233-88-1 de-6-MSA-pactamycate 
• 1403757-83-4 (S)-1-((1R,2R,3S,4S,5S)-1-amino-5-azido-3-((tertbutyldiphenylsilyloxy)methyl)-2,3-dihydroxy-2-methyl-4-(3-(prop-1-en-2-yl)phenylamino)cyclopentyl)ethyl dimethylcarbamate 
• 1403834-91-2 (1S,5R,6S,7S,8R)-6-azido-1-((tert-butyldiphenylsilyloxy)-methyl)-8-hydroxy-5-((S)-1-hydroxyethyl)-8-methyl-7-(3-(prop-1-en-2-yl)phenylamino)-2-oxa-4-azabicyclo[3.2.1]octan-3-one 
• 1403757-84-5 (S)-1-((1R,2R,3S,4S,5S)-1-amino-5-azido-2-(benzyloxy)-3-(benzyloxymethyl)-3-(tert-butyldiphenylsilyloxy)-2-methyl-4-(3-(prop-1-en-2-yl)phenylamino)cyclopentyl)ethyl 4-methoxybenzoate 
• 1403757-85-6 (S)-1-((1R,2R,3S,4S,5S)-1-amino-5-azido-2-(benzyloxy)-3-(benzyloxymethyl)-3-(tert-butyldiphenylsilyloxy)-2-methyl-4-(3-(prop-1-en-2-yl)phenylamino)cyclopentyl)ethanol 
• 1403757-86-7 (S)-1-((1R,2R,3S,4S,5S)-1-amino-5-azido-2-(benzyloxy)-3-(benzyloxymethyl)-3-(tert-butyldiphenylsilyloxy)-2-methyl-4-(3-(prop-1-en-2-yl)phenylamino)cyclopentyl)ethyl dimethylcarbamate 
• 1403757-87-8 (1S,2S,3R,4R,5S)-2-azido-4-(benzyloxy)-3-((S)-1-(benzyloxy)ethyl)-5-(benzyloxymethyl)-5-(tert-butyldiphenylsilyloxy)-4-methyl-N₁-(3-(prop-1-en-2-yl)phenyl)cyclopentane-1,3-diamine 
• 1403757-88-9 N-((1S,2S,3R,4R,5S)-5-azido-3-(benzyloxy)-4-((S)-1-(benzyloxy)ethyl)-2-(benzyloxymethyl)-2-(tert-butyldiphenylsilyloxy)-4-isocyanato-3-methylcyclopentyl)-3-(prop-1-en-2-yl)aniline 
• 1403757-89-0 3-((1R,2R,3S,4S,5S)-5-azido-2-(benzyloxy)-1-((S)-1-(benzyloxy)ethyl)-3-(benzyloxymethyl)-3-(tert-butyldiphenylsilyloxy)-2-methyl-4-(3-(prop-1-en-2-yl)phenylamino)cyclopentyl)-1,1-dimethylurea 
• 1403757-90-3 3-((1R,2R,3S,4S,5S)-4-(3-acetylphenylamino)-5-azido-2-(benzyloxy)-1-((S)-1-(benzyloxy)ethyl)-3-(benzyloxymethyl)-3-(tert-butyldiphenylsilyloxy)-2-methylcyclopentyl)-1,1-dimethylurea 
• 1403757-91-4 3-((1R,2R,3S,4S,5S)-4-(3-acetylphenylamino)-5-azido-2-(benzyloxy)-1-((S)-1-(benzyloxy)ethyl)-3-(benzyloxymethyl)-3-hydroxy-2-methylcyclopentyl)-1,1-dimethylurea 

Relevant articles and documents

Total synthesis of pactamycin and pactamycate: A detailed account

This article describes synthetic studies that culminated in the first total synthesis of pactamycin and pactamycate and, in parallel, the two known congeners, de-6-MSA-pactamycin and de-6-MSA-pactamycate, lacking the 6-methylsalicylyl moiety. Starting with l-threonine as a chiron, a series of stereocontrolled condensations led to a key cyclopentenone harboring a spirocyclic oxazoline. A series of systematic functionalizations led initially to the incorrect cyclopentanone epoxide, which was "inverted" under solvolytic conditions. Installation of the remaining groups and manipulation of the oxazoline eventually led to pactamycin, pactamycate, and their desalicylyl analogues.