129787-66-2

Basic information

• Product Name: FDGLU
• Synonyms: FDGLCA;FDGLCU;FDGLU;FLUORESCEIN DI-(BETA-D-GLUCOPYRANOSIDE);FLUORESCEIN DI-BETA-D-GLUCURONIDE;fluorescein di-(B-D-glucopyranoside);fluorescein di-(β-d-glucopyranoside);Fluorescein di(β-D-glucuronide)
• CAS NO: 129787-66-2
• Molecular Formula: C32H32O15
• Molecular Weight: 656.59
• EINECS: 1533716-785-6
• Mol File: 129787-66-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 974.8°C at 760 mmHg
• Flash Point: 316.5°C
• Appearance: /
• Density: 1.74g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.764
• Storage Temp.: −20°C
• BRN: 7455945
• CAS DataBase Reference: FDGLU(CAS DataBase Reference)
• NIST Chemistry Reference: FDGLU(129787-66-2)
• EPA Substance Registry System: FDGLU(129787-66-2)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10
• Hazardous Substances Data: 129787-66-2(Hazardous Substances Data)

Usage

Description

FDGLU, also known as Fluorescein Di-(β-D-glucopyranoside), is an off-white crystalline powder that serves as an ultrasensitive fluorogenic substrate. It is primarily used for the measurement of β-glucosidase activity, both in vivo and in vitro, due to its high sensitivity and specificity.

Uses

Used in Enzyme Activity Measurement:
FDGLU is used as a fluorogenic substrate for the measurement of β-glucosidase activity. Its application reason is its ultrasensitive nature, which allows for accurate and precise detection of enzyme activity levels in various biological samples.
Used in Pharmaceutical Research:
In the pharmaceutical industry, FDGLU is used as a research tool for the development of new drugs targeting β-glucosidase enzymes. Its application reason is its ability to provide valuable information on enzyme inhibition and activity, which can be crucial in the design and optimization of potential therapeutic agents.
Used in Diagnostic Applications:
FDGLU is also used in the development of diagnostic tests for various diseases and conditions, where β-glucosidase activity may serve as a biomarker. Its application reason is its high sensitivity, which enables the detection of even minor changes in enzyme activity that could indicate the presence of a specific disease or condition.
Used in Environmental Monitoring:
In the environmental sector, FDGLU can be employed as a tool for monitoring the presence and activity of β-glucosidase enzymes in various ecosystems. Its application reason is its ability to provide insights into the metabolic processes and health of microbial communities, which can be essential for understanding ecosystem dynamics and assessing environmental impacts.

InChI:InChI=1/C32H32O15/c33-11-21-23(35)25(37)27(39)30(45-21)42-13-5-7-17-19(9-13)44-20-10-14(43-31-28(40)26(38)24(36)22(12-34)46-31)6-8-18(20)32(17)16-4-2-1-3-15(16)29(41)47-32/h1-10,21-28,30-31,33-40H,11-12H2/t21-,22-,23-,24-,25+,26+,27-,28-,30-,31-/m1/s1