129825-11-2

Basic information

• Product Name: 4'-CHLORO-3'-(TRIFLUOROMETHYL)ACETOPHENONE
• Synonyms: 4'-CHLORO-3'-(TRIFLUOROMETHYL)ACETOPHENONE;4-CHLORO-3-(TRIFLUOROMETHYL)ACETOPHENONE;4'-Chloro-3'-(trifluoromethyl)acetophenone;5-Acetyl-2-chlorobenzotrifluoride, 1-[4-Chloro-3-(trifluoromethyl)phenyl]ethan-1-one;1-(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)ETHANONE
• CAS NO: 129825-11-2
• Molecular Formula: C₉H₆ClF₃O
• Molecular Weight: 222.59
• EINECS: -0
• Product Categories: Aromatic Acetophenones & Derivatives (substituted);Halogenated Heterocycles ,Isoquinolines ,Quinolines ,Quinazolines ,Quinaldines
• Mol File: 129825-11-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 61-63°C
• Boiling Point: 236.616 °C at 760 mmHg
• Flash Point: 96.902 °C
• Appearance: /
• Density: 1.337 g/cm³
• Vapor Pressure: 0.0469mmHg at 25°C
• Refractive Index: 1.466
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• CAS DataBase Reference: 4'-CHLORO-3'-(TRIFLUOROMETHYL)ACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-CHLORO-3'-(TRIFLUOROMETHYL)ACETOPHENONE(129825-11-2)
• EPA Substance Registry System: 4'-CHLORO-3'-(TRIFLUOROMETHYL)ACETOPHENONE(129825-11-2)

Safety Data

• Hazard Codes: Xi,F,Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• PackingGroup: I
• Hazardous Substances Data: 129825-11-2(Hazardous Substances Data)

Usage

Chemical Properties

white powder

InChI:InChI=1/C9H6ClF3O/c1-5(14)6-2-3-8(10)7(4-6)9(11,12)13/h2-4H,1H3

Upstream product

• 348-84-5 1-(4-chloro-3-trifluoromethyl-phenyl)-ethanol 
• 34328-46-6 4-chloro-3-(trifluoromethyl)benzaldehyde 

Downstream Products

• 866141-77-7 2-trifluoromethyl-4-acetylphenylboronic acid pinacol ester 
• 866141-78-8 1-[4-(6-cyclopropylmethyl-7-ethyl-4-methyl-7,8-dihydro-6H-1,3,6,8a-tetraaza-acenaphthylen-2-yl)-3-trifluoromethyl-phenyl]-ethanone 
• 866141-79-9 6-cyclopropylmethyl-7-ethyl-2-(4-isopropenyl-2-trifluoromethyl-phenyl)-4-methyl-7,8-dihydro-6H-1,3,6,8a-tetraaza-acenaphthylene 
• 1045771-63-8 2-(trimethylsilanyl)ethanesulfonic acid [4-acetyl-2-(trifluoromethyl)phenyl]amide 
• 1100768-05-5 1-(4-mercapto-3-trifluoromethyl-phenyl)-ethanone 
• 1192599-27-1 2-(1-(4-chloro-3-(trifluoromethyl)phenyl)ethylidene)hydrazinecarboximidamide hydrochloride 
• 1257310-75-0 (4-acetyl-2-trifluoromethylphenyl)carbamic acid 2-trimethylsilanylethyl ester 
• 1083076-04-3 carbamic acid 1-(4-chloro-3-trifluoromethyl-phenyl)-3-[4-(4-methoxy-phenyl)-piperazin-1-yl]-propyl ester 
• 1369891-72-4 C₂₁H₂₄ClF₃N₂O₂ 
• 1369892-26-1 C₂₁H₂₂ClF₃N₂O₂ 
• 240136-66-7 4-[4-chloro-3-(trifluoromethyl)phenyl]-1,3-thiazole-2-amine 

Relevant articles and documents

DERIVATIVES OF BENZOTHIAZINES, PREPARATION THEREOF AND APPLICATION THEREOF AS DRUGS

The object of the present invention is benzothiazine derivatives having the capability of inhibiting 11β-HSD1 not only at an enzymatic level but also at a cell level. The compounds of the present invention are of general formula (I). Wherein notably R1 represents a hydrogen or OR1 represents an ester or an ether. R2 represents a naphthyl or a 1, 2, 3, 4-tetrahydro-naphthalene or a biphenyl or phenyl pyridine or a substituted phenyl. R3 represents a methyl or ethyl; R4 and R'4 represent a hydrogen.

IMIDAZOLIUM CXCR3 INHIBITORS

Imidazolium compounds of formula (I); wherein: Aˉ is an anion; R1, R2 and R3 are the same or different and are hydrogen, C1-C6 alkyl, aryl, fused aryl, or heteroaryl; or are substituted aryl, fused ar