129835-18-3

Basic information

• Product Name: Adenosine, 2'-deoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]-
• CAS NO: 129835-18-3
• Molecular Formula: C26H31N5O3Si
• Molecular Weight: 489.649
• Mol File: 129835-18-3.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Adenosine, 2'-deoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Adenosine, 2'-deoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]-(129835-18-3)
• EPA Substance Registry System: Adenosine, 2'-deoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]-(129835-18-3)

Safety Data

• Hazardous Substances Data: 129835-18-3(Hazardous Substances Data)

Upstream product

• 129835-19-4 5'-O-tert-butyldiphenylsilyl-2'-deoxy-3'-ketoadenosine 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 958-09-8 2'-deoxy-D-adenosine 

Downstream Products

• 1235551-24-2 6-N-[(di-n-butylamino)methylene]-5'-O-(tert-butyldiphenylsilyl)-2'-deoxyadenosine 
• 149097-55-2 dibenzyl 5'-O-tert-butyldiphenylsilyl-2'-deoxy-3'-O-phosphonomethyladenosine 
• 149097-45-0 dibenzyl 2'-deoxy-N⁶-dimethylaminomethylene-5'-O-phosphonomethyl-3'-O-(tetrahydro-2H-pyran-2-yl)adenosine 
• 157729-45-8 9-[(2R,4R,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-((E)-styryl)-tetrahydro-furan-2-yl]-9H-purin-6-ylamine 
• 157729-47-0 (2S,3S,5R)-5-(6-Amino-purin-9-yl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-3-carbaldehyde 
• 128075-93-4 9-<5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-glycero-pentofuranosyl>adenine 
• 305819-98-1 9-(2-deoxy-3-C-phosphono-5-O-tert-butyldiphenylsilyl-β-D-threo-pentofuranosyl)adenine 
• 858672-65-8 9-[3-O-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2-deoxy-β-D-erythro-pentofuranosyl]adenine 

Relevant articles and documents

Mild Periodinane Oxidation of Protected Nucleosides to Give 2'- and 3'-Ketonucleosides. The First Isolation of a Purine 2'-Deoxy-3'-ketonucleoside Derivative

Oxidation of 3',5'- or 2',5'-bis-O-silyl-protected nucleosides with Dess-Martin 12-I-5 periodinane reagent, 1,1,1-tris(acetyloxy)-1,1-dihydro-1,2-benziodoxol-3(1H)-one (I), in dichloromethane gives 2'- or 3'-ketonucleoside derivatives, respectively.Isolation of the first purine 2'-deoxy-3'-ketonucleoside derivative (2d) has been accomplished by periodinane oxidation of 5'-O-(tert-butyldiphenylsilyl)-2'-deoxyadenosine (1d).

NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS

The present invention relates to novel phosphorous (V) (P(V)) reagents, methods for preparing thereof, and methods for preparing organophosphorous (V) compounds by using the novel reagents.

Synthesis of a deoxyxylopuromycin analogue

N6-Bis-demethylated deoxyxylopuromycin was synthesized over six steps in 56% overall yield. The key steps are Mitsunobu reaction with DPPA and a Staudinger-Vilarrasa coupling. Georg Thieme Verlag Stuttgart - New York.