129849-27-0Relevant articles and documents
Palladium Catalysis in Cephalosporin Chemistry: General Methodology for the Synthesis of Cephem Side Chains
Farina, Vittorio,Baker, Stephen R.,Benigni, Daniel A.,Hauck, Sheila I.,Sapino, Chester
, p. 5833 - 5847 (2007/10/02)
We describe in full the palladium-catalyzed coupling of 3-(triflyloxy)cephems with organotin compounds, leading to the synthesis of 3-alkenyl-, 3-alkynyl-, and 3-arylcephems under exceptionally mild conditions.While this approach was not satisfactory for