129855-33-0Relevant articles and documents
In vitro DNA binding, pBR322 plasmid cleavage and molecular modeling study of chiral benzothiazole Schiff-base-valine Cu(II) and Zn(II) complexes to evaluate their enantiomeric biological disposition for molecular target DNA
Alizadeh, Rahman,Afzal, Mohd,Arjmand, Farukh
, p. 625 - 635 (2014)
Bicyclic heterocyclic compounds viz. benzothiazoles are key components of deoxyribonucleic acid (DNA) molecules and participate directly in the encoding of genetic information. Benzothiazoles, therefore, represent a potent and selective class of antitumor
A benzimidazole/benzothiazole-based electrochemical chemosensor for nanomolar detection of guanine
Sharma, Hemant,Singh, Narinder,Jang, Doo Ok
, p. 6962 - 6969 (2015)
The electrochemical detection of guanine was accomplished using benzimidazole/benzothiazole-based imine-linked Co(iii) complexes 2, 4 and 6 with platinum electrodes. Linear sweep voltammetry (LSV), differential pulse voltammetry (DPV) and cyclic voltammet
Quantification of silver in several samples using a new ionophore polymer membrane as an optical sensor
Amin, Alaa S.,Askar, Abdelrazek M.,El-Feky, Hesham H.
, p. 35300 - 35310 (2021/11/30)
Growing concerns about the possible toxicity of silver to aquatic organisms, bacteria, and humans have led to newly issued regulations by the United States Environmental Protection Agency (US EPA) and the Food and Drug Administration (FDA) regarding the u
Mixed ligand complexes with 4-aminoantipyrine derivatives to combat natural antioxidant system: Synthesis, characterization and biological studies
Joseph,Rani, G. Ayisha Bibin
, p. 790 - 802 (2015/02/05)
Novel 4-aminoantipyrine based mixed ligand metal complexes with the Schiff bases of L1 (L1-4-aminoantipyrine with furfuraldehyde and L2/L3/L4/L5 are and L2-2-aminophenol with salicylaldehyde, L3-2-aminophenol with cinnamaldehyde, L4-2-aminobenzothiazole with salicylaldehyde, L5-2-aminobenzothiazole with cinnamaldehyde) were synthesized. The structures of the mixed ligand complexes were established by analytical and spectral techniques. They were screened for in vitro antimicrobial activity against of bacteria and fungi by disc diffusion method. The interaction of metal complexes with calf thymus-DNA (CT-DNA) was investigated by UV-visible, cyclic voltammetry, viscosity and thermal denaturation studies. DNA interaction studies suggest that metal complex binds to calf thymus-DNA through intercalation mode. Superoxide dismutase activity of these complexes has also been studied. The free ligands and their metal complexes have been tested for in vitro antioxidant activity by the reduction of 1,1-diphenyl-2-picryl hydrazyl (DPPH). The antioxidant activities of the complexes were studied and compared with the activity of ascorbic acid. Copper(II) complex showed superior antioxidant activity than other complexes.