129906-58-7Relevant articles and documents
Cobalt-Catalyzed Allylation of Amides with Styrenes Using DMSO as Both the Solvent and the α-Methylene Source
Zhang, Xu,Zhou, Zhi,Xu, Huiying,Xu, Xuefeng,Yu, Xiyong,Yi, Wei
supporting information, p. 7248 - 7253 (2019/10/08)
An efficient synthesis of privileged allylic amines has been developed via cobalt-catalyzed allylation of amides with styrenes, in which DMSO was used as both the solvent and the α-methylene source. This transformation features high yields, and selectivity for the (E)-isomer of the linear product. Through the experimental and computational investigations, a sequential K2S2O8-mediated oxidative coupling/cobalt-assisted regioselective alkene insertion/β-H elimination/alkene dissociation/hydride transfer process has also been deduced.