129994-09-8Relevant articles and documents
KINETICS OF REARRANGEMENT OF 2,4-DICHLOROPHENYL(1H-1,2,4-TRIAZOL-1-YLMETHYL)KETONE ENOL ACETATE
Krimer, M. Z.,Radul, O. M.,Margolin, L. N.,Feofanova, I. V.,Bogel'fer, L. Ya.,Negrebetskii, V. V.
, p. 1787 - 1789 (1992)
The kinetics of rearrangement of 2,4-dichlorophenyl(1H-1,2,4-triazol-1-ylmethyl)ketone enol acetate into 2,4-dichlorophenyl(5-acetyl-1H-1,2,4-triazol-1-ylmethyl)ketone were investigated by 1H NMR spectroscopy. It was shown that this rearrangement is a first-order reaction. The rate constant was measured in the 129-156 deg C range and the activation parameters of the reaction were determined. A hypothesis concerning the intramolecular character of the observed rearrangement was drawn based on the kinetic data. Keywords: enol acetate, rearrangement, kinetics, 2,4-dichlorophenyl(1H-1,2,4-triazol-1-ylmethyl)ketone, 2,4-dichlorophenyl(5-acetyl-1H-1,2,4-triazol-1-ylmethyl)ketone.
1,5-Rearrangement of enol acylates of aryl-1H-1,2,4-triazol-1-ylmethyl ketone
Radul, O. M.,Krimer, M. Z.,Rebrova, O. N.,Biyushkin, V. N.,Feofanova, I. V.,Panasenko, A. A.
, p. 522 - 527 (2007/10/02)
The rearrangement of enol acylates of aryl 1H-1,2,4-triazol-1-ylmethyl ketones at 140-150 deg C in acetic anhydride is studied.The migration of the acyl group to the C(5) atom of the heterocycle is found to be intramolecular.The characteristics of the original and final products are presented.X-ray structural studies of the enol acetates of 2,4-dichlorophenyl 1H-1,2,4-triazol-1-ylmethyl ketone and 2,4-dichlorophenyl 5-acetyl-1H-1,2,4-triazol-1-ylmethyl ketone are carried out.
