1300037-84-6

Basic information

• Product Name: 3-[(1R,2R)-1-Ethyl-2-Methyl-3-(MethylaMino)propyl]phenyl β-D-Glucopyranosiduronic Acid
• Synonyms: 3-[(1R,2R)-1-Ethyl-2-Methyl-3-(MethylaMino)propyl]phenyl β-D-Glucopyranosiduronic Acid;N-DesMethyl Tapentadol O-β-D-Glucuronide
• CAS NO: 1300037-84-6
• Molecular Formula: C19H29NO7
• Molecular Weight: 383.43606
• Product Categories: Amines;Aromatics;Glucuronides;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Amines, Aromatics, Glucuronides, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 1300037-84-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 597.5±50.0 °C(Predicted)
• Appearance: /
• Density: 1.297±0.06 g/cm3(Predicted)
• PKA: 2.79±0.70(Predicted)
• CAS DataBase Reference: 3-[(1R,2R)-1-Ethyl-2-Methyl-3-(MethylaMino)propyl]phenyl β-D-Glucopyranosiduronic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(1R,2R)-1-Ethyl-2-Methyl-3-(MethylaMino)propyl]phenyl β-D-Glucopyranosiduronic Acid(1300037-84-6)
• EPA Substance Registry System: 3-[(1R,2R)-1-Ethyl-2-Methyl-3-(MethylaMino)propyl]phenyl β-D-Glucopyranosiduronic Acid(1300037-84-6)

Safety Data

• Hazardous Substances Data: 1300037-84-6(Hazardous Substances Data)

Usage

Description

3-[(1R,2R)-1-Ethyl-2-Methyl-3-(MethylaMino)propyl]phenyl β-D-Glucopyranosiduronic Acid, also known as N-Desmethyl Tapentadol O-β-D-Glucuronide, is a glucuronide conjugate of N-Desmethyl Tapentadol (D294000) and a metabolite of Tapentadol (T007200). It is a complex organic compound with a unique structure that allows it to play a role in the metabolism of certain drugs.

Uses

Used in Pharmaceutical Industry:
3-[(1R,2R)-1-Ethyl-2-Methyl-3-(MethylaMino)propyl]phenyl β-D-Glucopyranosiduronic Acid is used as a metabolite in the pharmaceutical industry for its role in the metabolism of Tapentadol. It helps in understanding the drug's pharmacokinetics and pharmacodynamics, which is crucial for the development and optimization of drug therapies.
Used in Drug Metabolism Studies:
In drug metabolism studies, 3-[(1R,2R)-1-Ethyl-2-Methyl-3-(MethylaMino)propyl]phenyl β-D-Glucopyranosiduronic Acid serves as an important biomarker for the evaluation of drug metabolism pathways. Its analysis can provide insights into the metabolic fate of Tapentadol and contribute to the improvement of drug safety and efficacy.
Used in Toxicology Research:
3-[(1R,2R)-1-Ethyl-2-Methyl-3-(MethylaMino)propyl]phenyl β-D-Glucopyranosiduronic Acid is also used in toxicology research to investigate the potential toxic effects of Tapentadol and its metabolites. Understanding the toxicokinetics and toxicodynamics of this compound can help in assessing the safety profile of Tapentadol and guide the development of safer drug alternatives.