1300115-16-5

Basic information

• Product Name: N-chloroacetyl-2-aminophenylboronic acid pinacol ester
• Synonyms: N-chloroacetyl-2-aminophenylboronic acid pinacol ester
• CAS NO: 1300115-16-5
• Molecular Weight: 295.574
• Mol File: 1300115-16-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-chloroacetyl-2-aminophenylboronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-chloroacetyl-2-aminophenylboronic acid pinacol ester(1300115-16-5)
• EPA Substance Registry System: N-chloroacetyl-2-aminophenylboronic acid pinacol ester(1300115-16-5)

Safety Data

• Hazardous Substances Data: 1300115-16-5(Hazardous Substances Data)

Upstream product

• 79-04-9 chloroacetyl chloride 
• 191171-55-8 2-anilineboronic acid pinacol ester 

Downstream Products

• 1300115-17-6 N-iodoacetyl-2-aminophenylboronic acid pinacol ester 
• 1300115-18-7 2,4,6-Me₃-C₆H₂NHCH₂CONH(2-pinacolboryl-C₆H₄) 
• 1300115-23-4 2,6-iPr₂-C₆H₂NHCH₂CONH(2-pinacolboryl-C₆H₄) 
• 1300115-19-8 1-(2,4,6-trimethylphenyl)-3-(2-trifluoroboratophenyl)-4,5-dihydro-1H-imidazole 
• 1300115-24-5 1-(2,6-diisopropylphenyl)-3-(2-trifluoroboratophenyl)-4,5-dihydro-1H-imidazole 

Relevant articles and documents

Synthesis of trifluoroborate functionalised imidazolium salts as precursors to weakly coordinating bidentate NHC ligands

A new class of trifluoroborate functionalised N-heterocyclic carbene precursors have been synthesised, isolated and characterised structurally. The ligands were obtained via a serendipitous one-pot reaction in which deprotection, cyclisation and fluorination of boryl-functionalised diarylethylenediamine derivatives occur concurrently. Deprotonation of the imidazolium salts was found to yield the free carbene, though 18-crown-6 was found necessary to prevent further reactivity of the resulting aryl potassium trifluoroborate salts; in the absence of 18-crown-6, elimination of KF resulted in a cyclic carbene-BF2 arene adduct. Complexation to rhodium was facile, and yielded four-coordinate complexes in which the Rh-BF3 interaction was determined by 19F NMR spectroscopy to be weak.