130016-65-8 Usage
Derivative of pyrrolidine
2-(2,5-dimethyl-pyrrol-1-yl)-propionic acid is a modified version of the chemical pyrrolidine, which is a type of organic compound.
Non-steroidal anti-inflammatory drug (NSAID)
It is a drug that reduces inflammation and pain, and is commonly used to treat conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
Inhibits production of certain chemicals in the body
It works by inhibiting the production of chemicals in the body that cause inflammation and pain.
White, crystalline powder
This describes the physical appearance of the compound, which is a white powder that forms crystals.
Soluble in organic solvents
The compound dissolves easily in certain organic solvents, which are liquids used to dissolve other substances.
Molecular weight of 193.24 g/mol
This is the mass of one mole of the compound, which is a unit of measurement used in chemistry.
Important pharmaceutical ingredient
2-(2,5-dimethyl-pyrrol-1-yl)-propionic acid is used as an ingredient in pharmaceutical products due to its therapeutic applications in managing pain and inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 130016-65-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,0,1 and 6 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 130016-65:
(8*1)+(7*3)+(6*0)+(5*0)+(4*1)+(3*6)+(2*6)+(1*5)=68
68 % 10 = 8
So 130016-65-8 is a valid CAS Registry Number.
130016-65-8Relevant articles and documents
Peptide Synthesis Using the Pyrrole Ring as an Amino Protecting Group
Kashima, Choji,Maruyama, Tatsuya,Harada, Kazuo,Hibi, Shigeki,Omote, Yoshimori
, p. 601 - 645 (2007/10/02)
The utility of a pyrrole ring as an amino protecting group for amino acids in peptide synthesis has been studied.The N-termini of various amino acids (1) were protected with a pyrrole ring by treatment with 2,5-dimethoxytetrahydrofuran (10) to give 2-substituted 2-(1-pyrrolyl)acetic acids (11).The peptide bond between (11) and amino acid methyl ester (2) was formed using N,N'-dicyclohexylcarbodiimide, and the pyrrole ring was cleaved by ozonolysis and hydrolysis without the cleavage of a peptide bond to give the corresponding dipeptide compounds (26) in good yields.
