130049-16-0Relevant articles and documents
A convenient synthesis of functionalised 1-aryl-1,3-alkadiynes
Balova, Irina A.,Sorokoumov, Victor N.,Morozkina, Svetlana N.,Vinogradova, Olga V.,Knight, David W.,Vasilevsky, Sergey F.
, p. 882 - 888 (2005)
A two-step, one-pot synthesis of functionalised 1-arylalka-1,3-diynes is described. A key feature in this approach is exploitation of the "acetylene zipper" reaction to obtain terminal 1,3-alkadiynes 3 from internal isomers 1. Without isolation, but after
A one-pot synthesis of 1-arylalka-1,3-diynes by sequential acetylene zipper and Sonogashira reactions
Balova, Irina A.,Morozkina, Svetlana N.,Knight, David W.,Vasilevsky, Sergei F.
, p. 107 - 109 (2007/10/03)
1,3-Diynes, formed in situ by base-induced acetylene zipper reactions, following anion quenching with water, undergo smooth Sonogashira-type couplings with functionalized aryl iodides, to give good overall yields of 1-arylalka-1,3-diynes.
