13009-95-5 Usage
Description
5-Hydroxymethyldeoxycytidylic acid, also known as 5-hydroxymethyl-2'-deoxycytidine 5'-monophosphate, is a 2'-deoxycytidine phosphate compound with a phosphate group at the 5'-position and a hydroxymethyl substituent at the 5-position. It is a modified nucleotide that plays a crucial role in various biological processes.
Uses
Used in Pharmaceutical Industry:
5-Hydroxymethyldeoxycytidylic acid is used as an active pharmaceutical ingredient for the development of drugs targeting various diseases. Its unique structure allows it to interact with cellular machinery, making it a promising candidate for therapeutic applications.
Used in Research and Development:
In the field of research, 5-hydroxymethyldeoxycytidylic acid is used as a key compound for studying the mechanisms of DNA methylation and demethylation, which are essential for gene regulation and cellular function. It helps researchers understand the role of this modified nucleotide in various biological processes and its potential as a therapeutic target.
Used in Diagnostic Applications:
5-Hydroxymethyldeoxycytidylic acid can be employed as a biomarker in diagnostic tests to detect and monitor the presence of specific diseases or conditions. Its unique properties make it a valuable tool for the development of novel diagnostic methods.
Used in Drug Delivery Systems:
Similar to gallotannin, 5-hydroxymethyldeoxycytidylic acid can be incorporated into drug delivery systems to improve its bioavailability and therapeutic efficacy. By using various carriers, such as organic and metallic nanoparticles, the compound can be more effectively delivered to target cells, enhancing its potential for treating various diseases.
Used in Biochemical and Molecular Biology Applications:
5-Hydroxymethyldeoxycytidylic acid is also used in biochemical and molecular biology research as a substrate or probe for studying the enzymes involved in DNA methylation and demethylation. This helps researchers understand the molecular mechanisms underlying these processes and develop targeted therapies for diseases associated with aberrant DNA methylation patterns.
Check Digit Verification of cas no
The CAS Registry Mumber 13009-95-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,0 and 9 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 13009-95:
(7*1)+(6*3)+(5*0)+(4*0)+(3*9)+(2*9)+(1*5)=75
75 % 10 = 5
So 13009-95-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H16N3O8P/c11-9-5(3-14)2-13(10(16)12-9)8-1-6(15)7(21-8)4-20-22(17,18)19/h2,6-8,14-15H,1,3-4H2,(H2,11,12,16)(H2,17,18,19)/t6-,7+,8+/m0/s1
13009-95-5Relevant articles and documents
Efficient synthesis of 5-hydroxymethyl-, 5-formyl-, and 5-carboxyl-2′-deoxycytidine and their triphosphates
Sun, Qi,Sun, Jian,Gong, Shan-Shan,Wang, Cheng-Jun,Pu, Shou-Zhi,Feng, Fu-De
, p. 36036 - 36039 (2014)
An efficient P(V)-N activation strategy for the preparation of high-quality 5-hydroxymethyl-, 5-formyl-, and 5-carboxyl-2′-deoxycytidine triphosphates has been developed. The method was also optimized for gram-scale synthesis of the corresponding parent n
Oxidation of Cytosine and 5-Methylcytosine Nucleosides and 5-Methyl-2'-deoxycytidine 5'-Monophosphate with Peroxosulfate Ions
Itahara, Toshio
, p. 1591 - 1594 (2007/10/02)
Reaction of 5-methylcytosine nucleosides and nucleotide with Na2S2O8 resulted in an oxidation of the 5-methyl group, while treatment of them and cytosine nucleosides with KHSO5 gave the corresponding N3-oxides.