130145-45-8Relevant articles and documents
Novel trisubstituted benzimidazoles, targeting Mtb FtsZ, as a new class of antitubercular agents
Kumar, Kunal,Awasthi, Divya,Lee, Seung-Yub,Zanardi, Ilaria,Ruzsicska, Bela,Knudson, Susan,Tonge, Peter J.,Slayden, Richard A.,Ojima, Iwao
, p. 374 - 381 (2011/03/18)
Libraries of novel trisubstituted benzimidazoles were created through rational drug design. A good number of these benzimidazoles exhibited promising MIC values in the range of 0.5-6 μg/mL (2-15 μM) for their antibacterial activity against Mtb H37Rv strai
Potential Antimitotic Agents. Synthesis of Some Ethyl Benzopyrazin-7-ylcarbamates, Ethyl Pyridopyrazin-7-ylcarbamates, and Ethyl Pyrido-as-triazin-7-ylcarbamates
Temple, Carroll,Rener, Gregory A.
, p. 3044 - 3050 (2007/10/02)
Ring analogues and derivatives of the 1,2-dihydropyridopyrazin-7-ylcarbamates (e.g., 29), antimitotic agents with antitumor activity, were prepared in the search for compounds with greater selectivity.Methods were developed for the conversion of su