130169-01-6Relevant articles and documents
(Pyrimidinyloxy)acetic acids and pyrimidineacetic acids as a novel class of aldose reductase inhibitors
Ellingboe,Alessi,Millen,Sredy,King,Prusiewicz,Guzzo,VanEngen,Bagli
, p. 2892 - 2899 (2007/10/02)
Pyrimidineacetic acids and (pyrimidinyloxy)acetic acids were synthesized by alkylation, with methyl bromoacetate or tert-butyl bromoacetate as alkylating agents. Alkylation reaction at the nitrogen or oxygen atom for different substrates was found to be s