130182-88-6

Basic information

• Product Name: N-(4-(4-fluorophenyl)-3-butenyloxy)-phthalimide
• Synonyms: N-(4-(4-fluorophenyl)-3-butenyloxy)-phthalimide
• CAS NO: 130182-88-6
• Molecular Weight: 311.312
• Mol File: 130182-88-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-(4-fluorophenyl)-3-butenyloxy)-phthalimide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-(4-fluorophenyl)-3-butenyloxy)-phthalimide(130182-88-6)
• EPA Substance Registry System: N-(4-(4-fluorophenyl)-3-butenyloxy)-phthalimide(130182-88-6)

Safety Data

• Hazardous Substances Data: 130182-88-6(Hazardous Substances Data)

Upstream product

• 524-38-9 N-hydroxyphthalimide 
• 7515-50-6 (E)-4-(4-fluorophenyl)but-3-en-1-ol 

Downstream Products

• 135980-61-9 N-(4-(4-Fluorophenyl)-butoxy)-phthalimide 

Relevant articles and documents

Palladium-Catalyzed Tandem Hydrocarbonylative Lactamization and Cycloaddition Reaction for the Construction of Bridged Polycyclic Lactams

The intramolecular hydroaminocarbonylation of alkenes is a compelling tool to rapidly access lactam, a privileged motif ubiquitous in natural products, pharmaceuticals, and agrochemicals. However, selective carbonylation to bridged polycyclic lactams with a lactam nitrogen at a bridgehead position is less explored. We herein report a modular palladium-catalyzed approach to perform a tandem hydrocarbonylative lactamization/Diels-Alder cycloaddition reaction with 2-vinyl aryl aldimines, alkenes, and CO, which offers convenient access to furnish the bridged polycyclic lactams in high yields with high selectivities.