130219-85-1

Basic information

• Product Name: (5-Chloro-benzo[b]thiophen-3-ylmethyl)-((Z)-6,6-dimethyl-hept-2-en-4-ynyl)-methyl-amine
• Synonyms: (5-Chloro-benzo[b]thiophen-3-ylmethyl)-((Z)-6,6-dimethyl-hept-2-en-4-ynyl)-methyl-amine
• CAS NO: 130219-85-1
• Molecular Weight: 331.909
• Mol File: 130219-85-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (5-Chloro-benzo[b]thiophen-3-ylmethyl)-((Z)-6,6-dimethyl-hept-2-en-4-ynyl)-methyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (5-Chloro-benzo[b]thiophen-3-ylmethyl)-((Z)-6,6-dimethyl-hept-2-en-4-ynyl)-methyl-amine(130219-85-1)
• EPA Substance Registry System: (5-Chloro-benzo[b]thiophen-3-ylmethyl)-((Z)-6,6-dimethyl-hept-2-en-4-ynyl)-methyl-amine(130219-85-1)

Safety Data

• Hazardous Substances Data: 130219-85-1(Hazardous Substances Data)

Upstream product

• 19404-18-3 5-chloro-3-methylbenzo(b)thiophene 

Relevant articles and documents

Synthesis and Structure-Activity Relationship of Benzothienylallylamine Antimycotics

Benzothiophene analogues of the allylamine antimycotic terbinafine (2) bearing the side chain at various positions and optionally substituted by halogen have been prepared and their antifungal activity studied.Derivatives bearing the side chain at positions 3, 4, or 7 are bioequivalents of 2.Compounds containing the allylamine side chain at position 7, with a further substituent at position 3, showed significantly enhanced activity against Candida albicans, an effect which appears to be specifically linked only to this particular substitution pattern. 3-Chloro-7-benzothienyl derivative 7m was found to be the most potent allylamine antimycotic identified so far.In general, substituted benzothiophenes can be used not only as potential equivalents of naphthalene in bioactive compoudns but also as a tool to selectively modify biological activities.