130250-64-5

Basic information

• Product Name: (2S)-N-ethoxy-N-methyl-2-phenylbutanamide
• Synonyms: (2S)-N-ethoxy-N-methyl-2-phenylbutanamide
• CAS NO: 130250-64-5
• Molecular Weight: 207.272
• Mol File: 130250-64-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2S)-N-ethoxy-N-methyl-2-phenylbutanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-N-ethoxy-N-methyl-2-phenylbutanamide(130250-64-5)
• EPA Substance Registry System: (2S)-N-ethoxy-N-methyl-2-phenylbutanamide(130250-64-5)

Safety Data

• Hazardous Substances Data: 130250-64-5(Hazardous Substances Data)

Upstream product

• 4286-15-1 (S)-2-phenylbutyric acid 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 1117-97-1 N,0-dimethylhydroxylamine 

Relevant articles and documents

[Bis(2-methoxyethyl)amino]sulfur Trifluoride, the Deoxo-Fluor Reagent: Application toward One-Flask Transformations of Carboxylic Acids to Amides

The use of the Deoxo-Fluor reagent is a versatile method for acyl fluoride generation and subsequent one-flask amide coupling. It provides mild conditions and facile purification of the desired products in good to excellent yields. We have explored the utility of this reagent for the one-flask conversion of acids to amides and Weinreb amides and as a peptide-coupling reagent.

A CONVENIENT METHOD FOR THE PREPARATION OF N-METHOXYAMIDES

A variety of N-methoxyamides is easily prepared from carboxylic acids and N,O-dimethylhydroxylamine hydrochloride in the presence of triphenylphosphine and carbon tetrabromide.