130262-92-9

Basic information

• Product Name: 5Hydroxy Meloxicam
• Synonyms: 4-Hydroxy-N-[5-(hydroxyMethyl)-2-thiazolyl]-2-Methyl-2H-1,2-benzothiazine-3-carboxaMide 1,1-Dioxide;5'-HydroxyMethyl 5'-DesMethyl MeloxicaM
• CAS NO: 130262-92-9
• Molecular Formula: C14H13N3O5S2
• Molecular Weight: 367.405
• Product Categories: Metabolites
• Mol File: 130262-92-9.mol
• Article Data: 0

Chemical Properties

• Melting Point: 230-232°C
• Appearance: /
• Refractive Index: 1.747
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
• CAS DataBase Reference: 5Hydroxy Meloxicam(CAS DataBase Reference)
• NIST Chemistry Reference: 5Hydroxy Meloxicam(130262-92-9)
• EPA Substance Registry System: 5Hydroxy Meloxicam(130262-92-9)

Safety Data

• Hazardous Substances Data: 130262-92-9(Hazardous Substances Data)

Usage

Description

5-Hydroxy Meloxicam is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) Meloxicam. It is formed via metabolism of Meloxicam primarily by the cytochrome P450 (CYP) isoform CYP2C9 and to a lesser extent by CYP3A4. It is a yellow solid.

Uses

Used in Pharmaceutical Industry:
5-Hydroxy Meloxicam is used as a metabolite of Meloxicam for its potential therapeutic effects. It may have anti-inflammatory and analgesic properties, similar to its parent compound, Meloxicam. However, further research is needed to fully understand its potential applications and benefits.
Used in Research and Development:
5-Hydroxy Meloxicam is used as a research compound to study the metabolism and pharmacokinetics of Meloxicam. It can help researchers understand how Meloxicam is processed and eliminated from the body, which can be useful in optimizing its dosage and administration.
Used in Drug Metabolism Studies:
5-Hydroxy Meloxicam is used in drug metabolism studies to investigate the role of cytochrome P450 enzymes, particularly CYP2C9 and CYP3A4, in the metabolism of NSAIDs. This can provide valuable insights into the factors that influence the efficacy and safety of these drugs.
Used in Toxicology Studies:
5-Hydroxy Meloxicam can be used in toxicology studies to evaluate the potential toxic effects of Meloxicam and its metabolites. This can help in assessing the safety profile of Meloxicam and identifying any potential risks associated with its use.
Used in Drug Interaction Studies:
5-Hydroxy Meloxicam can be used in drug interaction studies to investigate the potential effects of other drugs on the metabolism of Meloxicam. This can help in identifying potential drug interactions and managing them appropriately to ensure patient safety.

InChI:InChI=1/C14H13N3O5S2/c1-17-11(13(20)16-14-15-6-8(7-18)23-14)12(19)9-4-2-3-5-10(9)24(17,21)22/h2-6,18-19H,7H2,1H3,(H,15,16,20)