130309-33-0 Usage
Description
N-Fmoc-D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid, commonly referred to as Fmoc-D-Tic-OH, is an amino acid derivative that plays a significant role in the field of peptide chemistry. It is characterized by its white crystalline powder form and is widely utilized for the synthesis of various peptides and proteins.
Uses
Used in Pharmaceutical Industry:
N-Fmoc-D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid is used as a building block for the synthesis of peptides and proteins. Its application is primarily due to its ability to facilitate the formation of peptide bonds, which are crucial for the structure and function of proteins.
Used in Research and Development:
In the field of research and development, N-Fmoc-D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid is employed as a key component in the design and synthesis of novel peptide-based therapeutics. Its use is driven by the need to explore new avenues for drug discovery and development, particularly in the areas of cancer, infectious diseases, and neurological disorders.
Used in Chemical Synthesis:
N-Fmoc-D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid is also used as an intermediate in the chemical synthesis of various compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its application in this context is due to its versatility and reactivity, which enable the creation of a wide range of products with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 130309-33-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,3,0 and 9 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 130309-33:
(8*1)+(7*3)+(6*0)+(5*3)+(4*0)+(3*9)+(2*3)+(1*3)=80
80 % 10 = 0
So 130309-33-0 is a valid CAS Registry Number.
InChI:InChI=1/C25H21NO4/c27-24(28)23-13-16-7-1-2-8-17(16)14-26(23)25(29)30-15-22-20-11-5-3-9-18(20)19-10-4-6-12-21(19)22/h1-12,22-23H,13-15H2,(H,27,28)/p-1/t23-/m1/s1
130309-33-0Relevant articles and documents
Solid-phase synthesis and utilization of side-chain reactive unnatural amino acids
O'Donnell, Martin J.,Alsina, Jordi,Scott, William L.
, p. 8403 - 8406 (2007/10/03)
Alkylation of the benzophenone imine of glycine Wang resin with α,ω-dihaloalkanes yielded valuable reactive intermediates. These racemic ω-chloro or ω-bromo intermediates were converted to α-amino acids containing diverse side-chain functionalities (e.g.
