13033-58-4

Basic information

• Product Name: 3-Chloropropyl Phenyl Sulfoxide
• Synonyms: 3-Chloropropyl Phenyl Sulfoxide
• CAS NO: 13033-58-4
• Molecular Weight: 202.705
• Mol File: 13033-58-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-Chloropropyl Phenyl Sulfoxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloropropyl Phenyl Sulfoxide(13033-58-4)
• EPA Substance Registry System: 3-Chloropropyl Phenyl Sulfoxide(13033-58-4)

Safety Data

• Hazardous Substances Data: 13033-58-4(Hazardous Substances Data)

Upstream product

• 2973-86-6 lithium thiophenoxide 
• 4911-65-3 3-chloropropyl phenyl sulfide 

Downstream Products

• 77400-50-1 3-Mercaptopropyl Phenyl Sulfoxide 
• 50337-59-2 cyclopropyl phenyl sulfoxide 
• 77400-56-7 3-<(2',4'-Dinitrophenyl)thio>propyl phenyl sulfoxide 
• 77400-54-5 C₁₈H₂₂O₃S₄ 
• 77400-52-3 1,10-Diphenyl-1,5,6,10-tetrathiadecane 1,10-Dioxide 
• 77400-51-2 1,10-Diphenyl-1,5,6,10-tetrathiadecane 1-Oxide 
• 77400-53-4 1,10-Diphenyl-1,5,6,10-tetrathiadecane 
• 19432-96-3 3-(phenylsulfonyl)propyl chloride 

Relevant articles and documents

Diastereoselective synthesis of tetrahydrofurans from Aryl 3-chloropropylsulfoxides and aldehydes

Carbanions of aryl 3-chloropropylsulfoxides react with nonenolizable aldehydes to give 2,3-disubstituted tetrahydrofurans. Deprotonation of the sulfoxides carried out in the presence of aldehydes results in the addition of the carbanions to the carbonyl group of the aldehydes, followed by 1,5-intramolecular substitution of the resulting aldol-type anion to produce the tetrahydrofuran ring. The 2-aryl and 3-arylsulfinyl substituents are always in trans relation, and the reaction proceeds with high diastereoselectivity also in respect to the chiral sulfur atom. The diastereoselectivity is attributed to the cyclic transition state of the aldol addition and increases when the aromatic ring of the sulfoxide contains electron-withdrawing substituents, whereas that of the aldehyde has electron-donating groups.

α-Fluorination of methyl phenyl sulfoxide and related compounds by molecular fluorine: A novel method for the introduction of fluorine into sulfoxides bearing α-H atoms

Direct formation of α-fluorosulfones from sulfoxides bearing α-H atoms merely by reaction with molecular fluorine (5% F2/N2) is reported, and a novel non-Pummerer-type mechanism is proposed for this α-fluorination reaction.