1303588-27-3

Basic information

• Product Name: 7-Chloro-1,2,3,4-tetrahydro-[1,8]naphthyridine
• Synonyms: 7-Chloro-1,2,3,4-tetrahydro-[1,8]naphthyridine
• CAS NO: 1303588-27-3
• Molecular Formula: C₈H₉ClN₂
• Molecular Weight: 168.62346
• Mol File: 1303588-27-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 7-Chloro-1,2,3,4-tetrahydro-[1,8]naphthyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Chloro-1,2,3,4-tetrahydro-[1,8]naphthyridine(1303588-27-3)
• EPA Substance Registry System: 7-Chloro-1,2,3,4-tetrahydro-[1,8]naphthyridine(1303588-27-3)

Safety Data

• Hazardous Substances Data: 1303588-27-3(Hazardous Substances Data)

Usage

Description

7-Chloro-1,2,3,4-tetrahydro-[1,8]naphthyridine is a chemical compound with the molecular formula C11H10ClN. It belongs to the class of naphthyridine derivatives and is a condensed ring system with a chloro substituent. 7-Chloro-1,2,3,4-tetrahydro-[1,8]naphthyridine is of interest to researchers and pharmaceutical companies due to its potential biological activities, including its role as an antibacterial and antifungal agent. It may also have potential applications in drug development and medicinal chemistry. Further research is being conducted to explore the various properties and uses of 7-Chloro-1,2,3,4-tetrahydro-[1,8]naphthyridine in different fields.

Uses

Used in Pharmaceutical Industry:
7-Chloro-1,2,3,4-tetrahydro-[1,8]naphthyridine is used as a pharmaceutical agent for its potential antibacterial and antifungal properties. It is being researched for its ability to combat various bacterial and fungal infections, offering a potential alternative or addition to existing treatments.
Used in Drug Development:
In the field of drug development, 7-Chloro-1,2,3,4-tetrahydro-[1,8]naphthyridine serves as a promising candidate for the creation of new medications. Its unique structure and biological activities make it a valuable compound for further exploration and development into potential therapeutic agents.
Used in Medicinal Chemistry:
7-Chloro-1,2,3,4-tetrahydro-[1,8]naphthyridine is utilized in medicinal chemistry for its potential to contribute to the discovery and design of novel drugs. Its chemical properties and interactions with biological targets make it a useful tool for researchers working on the development of new pharmaceuticals.

Upstream product

• 45644-21-1 6-chloropyridin-2-amine 
• 159603-71-1 t-butyl N-(6-chloro-2-pyridinyl)carbamate 

Downstream Products

• 1303588-28-4 7-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydro-1,8-naphthyridine 
• 1303583-59-6 N-(5-methylpyridin-3-yl)-7-(3-(trifluoromethyl)phenyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide 
• 1303588-29-5 tert-butyl 7-(3-(trifluoromethyl)phenyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate 
• 1303588-30-8 tert-butyl 4-oxo-7-(3-(trifluoromethyl)phenyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate 
• 1303588-31-9 7-(3-(trifluoromethyl)phenyl)-2,3-dihydro-1,8-naphthyridin-4(1H)-one 
• 1303585-87-6 4-oxo-N-(pyridin-4-yl)-7-(3-(trifluoromethyl)phenyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide 
• 1303588-32-0 4,4-difluoro-7-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydro-1,8-naphthyridine 
• 1303586-11-9 4,4-difluoro-N-(pyridin-4-yl)-7-(3-(trifluoromethyl)phenyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide 
• 1303586-83-5 4,4-difluoro-N-(pyridin-2-yl)-7-(3-(trifluoromethyl)phenyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide 

Relevant articles and documents

BICYCLIC PYRIDINES AND ANALOGS AS SIRTUIN MODULATORS

Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.