130400-03-2Relevant articles and documents
AN EFFICIENT ROUTE FOR THE STEREOSELECTIVE CONVERSION OF KETONES INTO THREE-CARBONS HOMOLOGATED PRIMARY E-ALLYLAMINES: THE PALLADIUM-CATALYSED REACTION OF VINYL TRIFLATES WITH N,N-DI-TERT-BUTOXYCARBONYL-N-ALLYAMINE.
Arcadi, A.,Bernocchi, E.,Cacchi, S.,Caglioti, L.,Marinelli, F.
, p. 2463 - 2466 (2007/10/02)
E-Allylamines N-protected with the easily removable tert-butoxycarbonyl group are stereoselectively prepared in good to high yield through the palladium-catalysed reaction of vinyl triflates with N,N-di-tert-butoxycarbonyl-N-allylamine in the presence of AcOK and n-Bu4NCl.The reaction is very sensitive to the nature of the base.The use of bases other than AcOK has been examined and proved to be unsuccessful.