130525-14-3Relevant articles and documents
Synthesis and antiarrhythmic activity of α-[(Diarylmethoxy)methyl]-1-piperidineethanols
Hoefle,Blouin,Fleming,Hastings,Hinkley,Mertz,Steffe,Stratton,Werbel
, p. 7 - 12 (2007/10/02)
A series of α-[(diarylmethoxy)methyl]-1-piperidineethanols was evaluated for antiarrhythmic activity in the coronary artery ligated dog model. Structure-activity relationship studies indicated that the 2,6-dimethylpiperidine group afforded the best antiar