130533-30-1

Basic information

• Product Name: (3-Chloro-isoquinolin-1-yl)-phenyl-acetonitrile
• CAS NO: 130533-30-1
• Molecular Weight: 278.741
• Mol File: 130533-30-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3-Chloro-isoquinolin-1-yl)-phenyl-acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (3-Chloro-isoquinolin-1-yl)-phenyl-acetonitrile(130533-30-1)
• EPA Substance Registry System: (3-Chloro-isoquinolin-1-yl)-phenyl-acetonitrile(130533-30-1)

Safety Data

• Hazardous Substances Data: 130533-30-1(Hazardous Substances Data)

Upstream product

• 19493-45-9 3-chloroisoquinoline 
• 140-29-4 phenylacetonitrile 

Relevant articles and documents

REACTIONS OF β-BROMO-N-HETEROAROMATICS WITH PHENYLACETONITRILE

The reaction of 3-bromopyridine with phenylacetonitrile in the presence of NaH in THF gave a simple substitution product, α-phenyl-3-pyridineacetonitrile, whereas the reaction of 5-bromopyrimidine with phenylacetonitrile under similar conditions gave a ring-transformation product, 2-amino-5-bromo-3-phenylpyridine. 3-Bromoquinoline and 4-bromoisoquinoline underwent the former type reaction, while 3-bromo- and 3-chloroisoquinolines were converted into 2-amino-3-phenyl-1-naphthalenecarbonitrile according to the latter type reaction.