130607-26-0 Usage
Description
Hydantocidin (52) is a microbial spironucleoside that selectively inhibits plant adenylsuccinate synthetase only after in vivo phosphorylation, resulting in the 5-monophosphate 52, an analog of adenosine 5-monophosphate (74).
Uses
Used in Pharmaceutical Industry:
Hydantocidin is used as a pharmaceutical compound for its selective inhibition of plant adenylsuccinate synthetase. This property makes it a potential candidate for the development of new drugs targeting specific plant enzymes, which could have applications in agriculture or other related fields.
Used in Research and Development:
Hydantocidin is used as a research tool for studying the structure and function of adenylsuccinate synthetase and its role in plant metabolism. Understanding the interaction between hydantocidin and this enzyme can provide valuable insights into the development of new drugs and therapies.
Used in Crop Protection:
Hydantocidin's ability to selectively inhibit plant adenylsuccinate synthetase could be utilized in the development of crop protection agents. By targeting specific plant enzymes, it may be possible to create compounds that protect crops from pests or diseases without harming the crop itself.
Used in Plant Metabolism Studies:
Hydantocidin can be used as a research tool to study plant metabolism and the role of adenylsuccinate synthetase in various metabolic pathways. This can help researchers better understand plant growth, development, and response to environmental stressors.
Check Digit Verification of cas no
The CAS Registry Mumber 130607-26-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,6,0 and 7 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 130607-26:
(8*1)+(7*3)+(6*0)+(5*6)+(4*0)+(3*7)+(2*2)+(1*6)=90
90 % 10 = 0
So 130607-26-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N2O6/c10-1-2-3(11)4(12)7(15-2)5(13)8-6(14)9-7/h2-4,10-12H,1H2,(H2,8,9,13,14)/t2-,3-,4-,7+/m1/s1
130607-26-0Relevant articles and documents
Syntheses of hydantocidin and C-2-thioxohydantocidin
Shiozaki, Masao
, p. 2077 - 2088 (2007/10/03)
Hydantocidin (12), a naturally occurring strong herbicide, was synthesized in 35.2% overall yield, with accompanying 5-epi-hydantocidin (12′) in 9.6% overall yield via isothiocyanate (13) and spiro-hydantoin (10) from 2,3-O-isopropylidene-D-ribono-1,4-lactone (1). C-2-Thioxo-hydantocidin (24) was also synthesized in 16.5% overall yield with accompanying 5-epi-C-2-thioxohydantocidin (24′, 9.2% yield) via isothiocyanate (22).
Novel synthesis of (+)-hydantocidin based on the plausible biosynthetic pathway
Nakajima, Noriyuki,Matsumoto, Miyoko,Kirihara, Masayuki,Hashimoto, Masaru,Katoh, Tadashi,Terashima, Shiro
, p. 1177 - 1194 (2007/10/03)
The title synthesis was examined by employing two synthetic schemes which feature N,O-spiroketal formation as a key step. Although the stepwise synthesis starting with D-fructose and proceeding through the D-psicose derivatives successfully produced a mixture of (+)-hydantocidin (1) and its C5-epimer [(-)-5-epihydantocidin (2)], the one-step synthesis utilizing D-isoascorbic acid and urea as starting materials was found to give 2 more selectively than 1. Studies on the key N,O-spiroketal formation and epimerization between 1 and 2 were also carried out to explore some novel aspects of the obtained results.
Natural Products as Pesticides: Two Examples of Stereoselective Synthesis
Frueh, Thomas,Chemla, Philippe,Ehrler, Juerg,Farooq, Saleem
, p. 37 - 48 (2007/10/03)
The strategy and synthetic efforts leading to efficient stereoselective syntheses of thiangazole, a tris-thiazolinyl-oxazole metabolite isolated from Polyangium spp., and hydantocidin, a spironucleoside metabolite isolated from Streptomyces hygroscopicus, are discussed.
