130614-23-2

Basic information

• Product Name: 2-(2-Bromophenyl)-1,3-dithiane
• Synonyms: 2-(2-Bromophenyl)-1,3-dithiane
• CAS NO: 130614-23-2
• Molecular Formula: C₁₀H₁₁BrS₂
• Molecular Weight: 275.22834
• Mol File: 130614-23-2.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2-Bromophenyl)-1,3-dithiane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Bromophenyl)-1,3-dithiane(130614-23-2)
• EPA Substance Registry System: 2-(2-Bromophenyl)-1,3-dithiane(130614-23-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 130614-23-2(Hazardous Substances Data)

Usage

Color

Colorless

State

Liquid

Composition

Dithiane ring with a bromophenyl group attached to one of the carbon atoms

Uses

Organic synthesis building block for pharmaceuticals, agrochemicals, and fine chemicals; reagent for introducing 2-(2-bromophenyl)-1,3-dithiane group into other molecules

Chemical Reactivity

Participates in various types of chemical reactions, making it a valuable tool in organic chemistry.

Upstream product

• 109-80-8 1.3-propanedithiol 
• 6630-33-7 ortho-bromobenzaldehyde 
• 57529-04-1 2-chloro-1,3-dithiane 

Downstream Products

• 130614-25-4 C₆H₄(2-Me₃SnCH₂)CHCH₂ 
• 6630-33-7 ortho-bromobenzaldehyde 
• 1188523-36-5 2-(2-(4-methoxybenzyl)phenyl)-1,3-dithiane 

Relevant articles and documents

Simultaneous and stereoselective formation of planar and axial chiralities in enantiopure sulfinyl iron diene complexes

(Matrix presented) Enantiopure (1Z,3E)-1-sulfinyl dienes bearing an o-dithianylphenyl group can be prepared and complexed with (bda)Fe(CO) 3 to afford the corresponding sulfinyl diene iron(0) tricarbonyl complexes. This diastereoselective compl

Visible-light mediated facile dithiane deprotection under metal free conditions

Visible light mediated facile and selective dithiane deprotection under metal free conditions is developed. Eosin Y (1 mol%) proved to be an effective catalyst for the dithiane deprotection under the ambient photoredox conditions. The standard household compact fluorescent light source (CFL bulb) proved to be effective under open-air conditions in aqueous acetonitrile at room temperature. The protocol that exhibits a broad substrate scope and functional group tolerance has been shown to expand to a range of transformations for the electron-rich and -deficient thioacetals and thioketals. The synthetic utility of this protocol has also been demonstrated by gram-scale application.

Direct anodic (thio)acetalization of aldehydes with alcohols (thiols) under neutral conditions, and computational insight into the electrochemical formation of the acetals

A versatile protocol for the production of acetals/thioacetals by means of direct electrochemical oxidation is developed here under neutral conditions, providing (thio)acetals with good functional group tolerance and a wide scope for both aldehydes and (thio)alcohols. DFT calculations reveal that direct electron transfer from the anode plays a key role in carbonyl activation during this acid free acetalization process.

Visible-light promoted dithioacetalization of aldehydes with thiols under aerobic and photocatalyst-free conditions

A novel photocatalyst-free visible-light-mediated dithioacetalization of aldehydes and thiols has been developed. This protocol is operationally simple, mild and atom-economical, which provides an environmental benign access to dithioacetals at room temperature under aerobic conditions.