130633-33-9

Basic information

• Product Name: (R)-tert-Butoxycarbonylamino-{3-[5-((2S,5R)-5-isopropyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-yl)-3-methoxy-2-methyl-phenoxy]-phenyl}-acetic acid methyl ester
• Synonyms: (R)-tert-Butoxycarbonylamino-{3-[5-((2S,5R)-5-isopropyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-yl)-3-methoxy-2-methyl-phenoxy]-phenyl}-acetic acid methyl ester
• CAS NO: 130633-33-9
• Molecular Weight: 583.682
• Mol File: 130633-33-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-tert-Butoxycarbonylamino-{3-[5-((2S,5R)-5-isopropyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-yl)-3-methoxy-2-methyl-phenoxy]-phenyl}-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-tert-Butoxycarbonylamino-{3-[5-((2S,5R)-5-isopropyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-yl)-3-methoxy-2-methyl-phenoxy]-phenyl}-acetic acid methyl ester(130633-33-9)
• EPA Substance Registry System: (R)-tert-Butoxycarbonylamino-{3-[5-((2S,5R)-5-isopropyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-yl)-3-methoxy-2-methyl-phenoxy]-phenyl}-acetic acid methyl ester(130633-33-9)

Safety Data

• Hazardous Substances Data: 130633-33-9(Hazardous Substances Data)

Upstream product

• 25698-27-5 (R)-3-hydroxyphenylglycine 
• 3260-88-6 1-chloro-3-methoxy-2-methylbenzene 
• 109838-85-9 (2R)-2,5-dihydro-2-isopropyl-3,6-dimethoxypyrazine 
• 130633-31-7 (R)-N-tert-butoxycarbonyl-3-hydroxyphenylglycine methyl ester 
• 87-60-5 3-chloro-2-methylbenzenamine 
• 130697-96-0 3-hydroxyphenylglycine methyl ester 

Downstream Products

• 130633-35-1 (S)-Amino-{3-[3-((R)-amino-methoxycarbonyl-methyl)-phenoxy]-5-methoxy-4-methyl-phenyl}-acetic acid methyl ester 
• 130633-34-0 (S)-Amino-{3-[3-((R)-tert-butoxycarbonylamino-methoxycarbonyl-methyl)-phenoxy]-5-methoxy-4-methyl-phenyl}-acetic acid methyl ester 

Relevant articles and documents

Synthesis of a Deoxyristomycinic Acid Derivative using Organomanganese Chemistry

Coupling of (3-chloro-2-methylanisole)tricarbonylmanganese tetrafluoroborate with the phenoxide derived from methyl N-Boc-3-hydroxyphenylglycinate gave the diaryl ether manganese complex (6).This complex underwent regiospecific, stereoselective reaction with Schollkopf's chiral glycine enolate equivalent to give a mixture of dienyl-Mn(CO)3 complexes that were converted in a two-step sequence into the protected deoxyristomycinic acid derivative (12).