130677-18-8

Basic information

• Product Name: [(4-trimethylstannyl)phenyl]methanol
• Synonyms: [(4-trimethylstannyl)phenyl]methanol
• CAS NO: 130677-18-8
• Molecular Weight: 270.946
• Mol File: 130677-18-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [(4-trimethylstannyl)phenyl]methanol(CAS DataBase Reference)
• NIST Chemistry Reference: [(4-trimethylstannyl)phenyl]methanol(130677-18-8)
• EPA Substance Registry System: [(4-trimethylstannyl)phenyl]methanol(130677-18-8)

Safety Data

• Hazardous Substances Data: 130677-18-8(Hazardous Substances Data)

Upstream product

• 873-75-6 4-bromobenzenemethanol 
• 1066-45-1 trimethyltin(IV)chloride 
• 661-69-8 hexamethyldistannane 

Downstream Products

• 154352-41-7 methyl 2-[(4-hydroxymethyl)phenyl]-3-pyridinecarboxylate 
• 90972-59-1 [4-(bromomethyl)phenyl]trimethyl stannane 
• 130677-17-7 p-Nitrobenzyl-(5 R ,6 S)-2-(4-hydroxymethylphenyl)-6-[1 R-(trimethylsilyloxy)ethyl]carbapen-2-em-3-carboxylate 

Relevant articles and documents

Comparative analysis of the olfactory properties of silicon/germanium/tin analogues of the lily-of-the-valley odorants lilial and bourgeonal

The silicon/germanium/tin analogues of the lily-of-the-valley odorants lilial (rac-1a), compounds rac-1b, rac-1c, and rac-1d, and bourgeonal (2a), compounds 2b, 2c, and 2d, were synthesized and characterized for their olfactory properties, including GC-olfactometry studies. Compounds rac-1a-c and 2a-c possess a typical lily-of-the-valley odor, whereas the stanna-analogues rac-1d and 2d, despite some floral aspects, clearly no longer belong to the lily-of-the-valley family. In both series of the carbon/silicon/germanium/tin analogues studied, the lily-of-the-valley odor decreases in the order of carbon2+ imaging. Bourgeonal (2a) showed the highest activation potency, whereas lilial (rac-1a) and sila-bourgeonal (2b) exhibited lower activation potencies. Sila-lilial (rac-1b), germa-lilial (rac-1c), and stanna-lilial (rac-1d), as well as germabourgeonal (2c) and stanna-bourgeonal (2d), did not activate heterologously expressed hOR17-4 at the concentrations tested. The carbon/silicon/germanium/tin switch strategy thus showed that the stanna-derivatives clearly exceeded the molecular dimensions of the odorant receptor(s) responsible for the recognition of lily-of-the-valley odorants, although the receptor affinity was already affected with the sila- and germaanalogues. These data could later be used in the qualitative and quantitative evaluation of computational receptor models.

Novel synthesis of carbapenem intermediates

Carbapenems having the formula: are prepared by a novel reaction of a readily accessible carbapenem intermediate and an organostannane. The reaction, which is mediated by a palladium compound and, optionally, a phosphine ligand, proceeds at remarkably mild temperatures in reproducibly good yields.