13068-12-7Relevant articles and documents
Discovery, synthesis,andevaluation of small-molecule signal transducer and activator of transcription 3 inhibitors
Shi, Zhi-Bing,Zhao, Dan,Huang, Yan-Yan,Du, Yun,Cao, Xiang-Rong,Gong, Zhu-Nan,Zhao, Rui,Li, Jian-Xin
, p. 1574 - 1580 (2013/02/23)
The signal transducer and activator of transcription 3 (STAT3) oncogene is a promising molecular target and its inhibitors have great potential as anticancer drugs. To identify novel and STAT3-selective inhibitors, a virtual screening based on Specs and M
Synthesis of Pyrrazoles and Pyrazolopyrimidines from 3-Arylsulfonylaminoacrylates
McFadden, Helen G.,Huppatz, John L.,Halladay, Peter K.
, p. 873 - 886 (2007/10/02)
3-Arylsulfonylaminopyrazole-4-carboxamides and -carboxylates were synthesized from 3-arylsulfonylamino-3-methylthiocyanoacrylate derivatives as potential herbicidal inhibitors of the enzyme acetohydroxyacetic acid synthase (AHAS). Some of these compounds
PYRIDYL GUANIDINE ANTI-ULCER AGENTS
-
, (2008/06/13)
Compounds of the formula STR1 wherein R 1 is a straight or branched chain alkynyl group containing from 3 to 9 carbon atoms, inclusive; R 2 is hydrogen, hydroxy, cyano, (lower)alkyl, (lower) alkoxy, halogen or amino; n is 2 or 3; X is NR 3 or CHR 3 ; R 3