130799-18-7

Basic information

• Product Name: 5β,6α-dibenzyloxypolyangioic acid
• Synonyms: 5β,6α-dibenzyloxypolyangioic acid
• CAS NO: 130799-18-7
• Molecular Weight: 654.887
• Mol File: 130799-18-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5β,6α-dibenzyloxypolyangioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5β,6α-dibenzyloxypolyangioic acid(130799-18-7)
• EPA Substance Registry System: 5β,6α-dibenzyloxypolyangioic acid(130799-18-7)

Safety Data

• Hazardous Substances Data: 130799-18-7(Hazardous Substances Data)

Upstream product

• 130799-12-1 (E)-(S)-2-((2R,6R)-6-Ethyl-5-methyl-3,6-dihydro-2H-pyran-2-yl)-pent-3-en-2-ol 
• 130799-00-7 methyl 2,3-di-O-benzyl-4-deoxy-α-D-glucopyranosiduronic acid 
• 130798-99-1 methyl 2,3-di-O-benzyl-6-O-t-butyldiphenylsilyl-4-deoxy-α-D-glucopyranoside 
• 17791-36-5 methyl 2,3-di-O-benzyl-α-D-glucopyranoside 
• 130856-15-4 (+)-(2R,6R)-6-ethyl-5-methyl-3,6-dihydro-2H-pyran-2-yl carboxylic acid 
• 130799-19-8 (+/-)-cis-6-ethyl-5-methyl-3,6-dihydro-2H-pyran-2-carboxylic acid 
• 130799-02-9 methyl (methyl 2,3-di-O-benzyl-4-deoxy-α-D-glucoheptopyranosiduronate) 
• 130799-01-8 1-((2S,4S,5R,6S)-4,5-Bis-benzyloxy-6-methoxy-tetrahydro-pyran-2-yl)-2-diazo-ethanone 
• 130798-97-9 methyl 2,3-di-O-benzyl-1,4-dideoxy-1α/1β-fluoro-D-glucoheptopyranuronate 
• 130799-14-3 (E)-(R)-5-((2R,6R)-6-Ethyl-5-methyl-3,6-dihydro-2H-pyran-2-yl)-3-methyl-hex-4-enoic acid methyl ester 
• 130799-13-2 (E)-(R)-5-((2R,6R)-6-Ethyl-5-methyl-3,6-dihydro-2H-pyran-2-yl)-3-methyl-hex-4-enoic acid 
• 130799-11-0 (E)-1-((2R,6R)-6-Ethyl-5-methyl-3,6-dihydro-2H-pyran-2-yl)-but-2-en-1-one 
• 105247-06-1 (E)-3-methyl-1,3-hexadiene 
• 153618-43-0 {(2S,4S,5R,6S)-4,5-Bis-benzyloxy-6-[(E)-2-((1S,2S,3S)-2-hydroxymethyl-3-methyl-cyclopropyl)-vinyl]-tetrahydro-pyran-2-yl}-acetic acid methyl ester 

Downstream Products

• 58857-02-6 (+)-ambruticin S 

Relevant articles and documents

Total synthesis of natural (+)-ambruticin

The structurally unique antifungal antibiotic ambruticin (1) has been prepared for the first time in a convergent synthesis. The strategy for its synthesis involved the independent preparation of the enantiomerically pure fragments 19, 31 and 49. The required C(7) - C(8) β-C-glycoside bond was formed by coupling the glycosyl fluoride 19 with the in situ formed vinyl alane derivative 32. Formation of the C(13) - C(14) trans double bond was accomplished by condensation of the sulfone fragment 49 with the aldehyde intermediate 35 leading to the complete skeletal framework of ambruticin. Saponification of 51 and then cleavage of the benzyl protecting groups gave natural ambruticin.