130800-83-8Relevant articles and documents
Herbicidal 3-(substituted-benzyl)-1-methyl-6-trifluoromethyluracils
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, (2008/06/13)
Herbicidal 3-(substituted-benzyl)-1-methyl-6-trifluoromethyluracils, compositions containing them, and methods of using them to control undesired plant growth, including use to control weeds in certain crops, are disclosed. The herbicidal compounds of the present invention are defined by the following generic structure: STR1 in which V is hydrogen, halogen, nitro, amino, alkoxy, alkyl, cyano, phenyl, alkylcarbonylamino, alkylsulfinyl, or haloalkyl; W is hydrogen, halogen, alkyl, alkoxy, alkylaminocarbonyl, propargyloxy, cyano, nitro, benzoyl, aminooxycarbonyl, alkylsulfonyl, alkoxyiminoalkyl, alkylthio or alkylsulfinyl; X is hydrogen, chlorine, alkoxy, nitro, or amino; Y is hydrogen, halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, alkoxyalkyl, alkylthio, alkylthioalkyl, alkenyl, acyl, epoxyalkyl, cyano, alkylaminocarbonyl, carboxy, formyl, hydroxy, hydroxyalkyl, haloalkylsulfonyloxy, benzoyl, aminooxycarbonyl, alkoxycarbonyl, propargyloxy, alkylsulfonyl, alkylsulfinyl, alkoxyiminoalkyl, or dialkylaminocarbonylthio; X and Y taken together are --OCH2 O-- or --OC(CH3)2 O--, where halogen is bromine, chlorine, fluorine, or iodine, and each aliphatic moiety has one to three carbon atoms.
Pharmacologically active CNS compound
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, (2008/06/13)
The invention provides a series of compounds of formula (I) and salts thereof, wherein for example,R1 and R2, which may be the same or different each represent -NR13R14 where R13 and R14 may each independently represent hydrogen or alkyl or, taken together with the nitrogen atom to which they are attached form a heterocyclic ring, optionally substituted by one or more alkyl or arylalkyl groups and optionally containing a further heteroatom;, R3 is hydrogen, haloalkyl, alkoxymethyl or alkyl;, R4 is hydrogen, nitro or halo;, R5 is hydrogen or halo;, R6 is hydrogen, halo, nitro, amino, alkylamino or dialkylamino;, R7 is hydrogen or halo;, R8 is hydrogen or halo; The compounds may be used for the treatment or prophylaxis of a neurodegenerative or other neurological disorder of the CNS, the aetiology or which includes excessive release of the neurotransmitter glutamate.