13081-74-8 Usage
Description
(4-METHYLBENZYL)PHOSPHONIC ACID, with the chemical formula C8H11O3P, is a phosphonic acid compound featuring a benzene ring with a methyl group and a phosphonic acid functional group. This versatile chemical is known for its strong binding and chelating properties due to the presence of the phosphonic acid group, making it a valuable component in various industrial applications.
Uses
Used in Pharmaceutical Industry:
(4-METHYLBENZYL)PHOSPHONIC ACID is used as an intermediate for the synthesis of various pharmaceutical compounds. Its strong chelating properties allow it to form stable complexes with metal ions, which can be beneficial in the development of drugs with enhanced stability and bioavailability.
Used in Agrochemical Industry:
(4-METHYLBENZYL)PHOSPHONIC ACID is used as a building block in the production of agrochemicals, such as pesticides and fertilizers. Its ability to chelate metal ions can help improve the effectiveness and longevity of these products, leading to better crop protection and yield.
Used in Polymer Industry:
(4-METHYLBENZYL)PHOSPHONIC ACID is used as a monomer in the synthesis of polymers with specific properties, such as flame retardancy or self-healing capabilities. The phosphonic acid group can provide these polymers with enhanced thermal stability and resistance to degradation.
Used as a Chelating Agent:
(4-METHYLBENZYL)PHOSPHONIC ACID is used as a chelating agent in metal ion sequestration. Its strong binding properties enable it to form stable complexes with metal ions, which can be useful in various chemical processes, such as water treatment, to remove harmful metal ions from the environment.
Used as a Corrosion Inhibitor:
(4-METHYLBENZYL)PHOSPHONIC ACID is used as a corrosion inhibitor in the protection of metals from degradation. Its chelating properties allow it to form a protective layer on the metal surface, preventing corrosion and extending the lifespan of metal components in various industries, such as automotive, aerospace, and construction.
Check Digit Verification of cas no
The CAS Registry Mumber 13081-74-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,8 and 1 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 13081-74:
(7*1)+(6*3)+(5*0)+(4*8)+(3*1)+(2*7)+(1*4)=78
78 % 10 = 8
So 13081-74-8 is a valid CAS Registry Number.
13081-74-8Relevant articles and documents
Designing anti-inflammatory drugs from parasitic worms: A synthetic small molecule analogue of the acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis
Al-Riyami, Lamyaa,Pineda, Miguel A.,Rzepecka, Justyna,Huggan, Judith K.,Khalaf, Abedawn I.,Suckling, Colin J.,Scott, Fraser J.,Rodgers, David T.,Harnett, Margaret M.,Harnett, William
, p. 9982 - 10002 (2014/01/17)
In spite of increasing evidence that parasitic worms may protect humans from developing allergic and autoimmune diseases and the continuing identification of defined helminth-derived immunomodulatory molecules, to date no new anti-inflammatory drugs have been developed from these organisms. We have approached this matter in a novel manner by synthesizing a library of drug-like small molecules based upon phosphorylcholine, the active moiety of the anti-inflammatory Acanthocheilonema viteae product, ES-62, which as an immunogenic protein is unsuitable for use as a drug. Following preliminary in vitro screening for inhibitory effects on relevant macrophage cytokine responses, a sulfone-containing phosphorylcholine analogue (11a) was selected for testing in an in vivo model of inflammation, collagen-induced arthritis (CIA). Testing revealed that 11a was as effective as ES-62 in protecting DBA/1 mice from developing CIA and mirrored its mechanism of action in downregulating the TLR/IL-1R transducer, MyD88. 11a is thus a novel prototype for anti-inflammatory drug development.
