1308668-88-3

Basic information

• Product Name: 2-chloro-4-[5-fluoro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-benzonitrile
• Synonyms: 2-chloro-4-[5-fluoro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-benzonitrile
• CAS NO: 1308668-88-3
• Molecular Weight: 276.698
• Mol File: 1308668-88-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-4-[5-fluoro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-4-[5-fluoro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-benzonitrile(1308668-88-3)
• EPA Substance Registry System: 2-chloro-4-[5-fluoro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-benzonitrile(1308668-88-3)

Safety Data

• Hazardous Substances Data: 1308668-88-3(Hazardous Substances Data)

Upstream product

• 548797-51-9 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile 
• 1308669-73-9 1-(3-bromo-5-fluoropyridin-4-yl)ethanol 
• 407-20-5 3-bromo-5-fluoropyridine 
• 154607-01-9 4-bromo-2-chlorobenzonitrile 

Downstream Products

• 1308668-97-4 2-chloro-4-[5-fluoro-4-((S)-1-hydroxy-ethyl)-pyridin-3-yl]-benzonitrile 
• 1308668-93-0 2-chloro-4-[5-fluoro-4-((R)-1-hydroxy-ethyl)-pyridin-3-yl]-benzonitrile 

Relevant articles and documents

ARYL-PYRIDINE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5 and n are defined herein. The invention also relates to a method for manufacturing compounds of the invention, and their therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.