130891-01-9

Basic information

• Product Name: Benzene, 1-bromo-3-[(phenylsulfonyl)methyl]-
• CAS NO: 130891-01-9
• Molecular Formula: C13H11BrO2S
• Molecular Weight: 311.199
• Mol File: 130891-01-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzene, 1-bromo-3-[(phenylsulfonyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-bromo-3-[(phenylsulfonyl)methyl]-(130891-01-9)
• EPA Substance Registry System: Benzene, 1-bromo-3-[(phenylsulfonyl)methyl]-(130891-01-9)

Safety Data

• Hazardous Substances Data: 130891-01-9(Hazardous Substances Data)

Upstream product

• 823-78-9 meta-bromobenzyl bromide 
• 873-55-2 sodium benzenesulfonate 
• 25932-11-0 benzenesulfinic acid sodium dihydrate 

Downstream Products

• 473580-39-1 1-(3-bromophenyl)-2-(3-chlorophenyl)ethyne 
• 153404-57-0 1-(3-bromophenyl)-2-(4-bromophenyl)ethyne 
• 14064-45-0 (E)-3-bromostilbene 
• 153404-60-5 1,2-bis(3-bromophenyl)acetylene 
• 23958-26-1 trans-1,2-bis(3-bromophenyl)ethene 
• 832744-38-4 3-[2-(3-bromophenyl)ethynyl]-1-[2-(4-hexylphenyl)ethynyl]benzene 
• 848072-81-1 [1-(3-benzenesulfonylmethyl-phenyl)-2-bromo-ethoxy]-tert-butyl-dimethyl-silane 
• 848072-80-0 1-(3-benzenesulfonylmethyl-phenyl)-ethanone 
• 292868-55-4 1-(2-bromophenyl)-2-(3-bromophenyl)ethyne 
• 473580-42-6 1-(3-bromophenyl)-2-(4-chlorophenyl)ethyne 

Relevant articles and documents

Syntheses of diarylethenes by perylene-catalyzed photodesulfonylation from ethenyl sulfones

Diarylethenes were obtained from the corresponding ethenyl sulfones by photocatalyzed desulfonylation using UV or blue LEDs. When perylene and i-Pr2NEt were used as a photocatalyst and a sacrificing reagent, respectively, this desulfonylation proceeded smoothly to afford the desired ethenes with the functional groups such as chloro, alkoxy and heteroaromatic rings remaining untouched. The use of a flow photoreactor enabled this desulfonylation to proceed more rapidly to finish in an hour of residence time.

Tryptamine-based human β3-adrenergic receptor agonists. Part 3: Improved oral bioavailability via modification of the sulfonamide moiety

The continued SAR investigation of tryptamine-based human β3-adrenergic receptor (AR) agonists is reported. Prior efforts resulted in the identification of 2 as a potent β3-AR agonist. Further modification of the left side arylsulfonamide portion in 2 provided compounds with good cell permeability, which have potent agonistic activity for β3-AR. Cinnamylamine analog 16i exhibited an excellent agonistic profile in vitro and good oral bioavailability in rats.

Sulfoximine version of double elimination protocol for synthesis of chiral acetylenic cyclophanes

A new strategy for constructing enantiopure acetylenic cyclophanes is described on the basis of one-pot double elimination reaction starting from dialdehydes and bis(sulfoximine)s. In this case, the conventional sulfone protocol affords poorer yields of t