13093-87-3

Basic information

• Product Name: 5-benzyl-2,2-dimethyl-2,3,7,7a-tetrahydroimidazo[5,1-b][1,3]thiazole-3,7-dicarboxylic acid
• CAS NO: 13093-87-3
• Molecular Formula: C₁₆H₁₈N₂O₄S
• Molecular Weight: 334.3901
• Mol File: 13093-87-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 620.3°C at 760 mmHg
• Flash Point: 329°C
• Density: 1.47g/cm³
• Vapor Pressure: 3E-16mmHg at 25°C
• Refractive Index: 1.691
• CAS DataBase Reference: 5-benzyl-2,2-dimethyl-2,3,7,7a-tetrahydroimidazo[5,1-b][1,3]thiazole-3,7-dicarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-benzyl-2,2-dimethyl-2,3,7,7a-tetrahydroimidazo[5,1-b][1,3]thiazole-3,7-dicarboxylic acid(13093-87-3)
• EPA Substance Registry System: 5-benzyl-2,2-dimethyl-2,3,7,7a-tetrahydroimidazo[5,1-b][1,3]thiazole-3,7-dicarboxylic acid(13093-87-3)

Safety Data

• Hazardous Substances Data: 13093-87-3(Hazardous Substances Data)

Usage

General Description

5-benzyl-2,2-dimethyl-2,3,7,7a-tetrahydroimidazo[5,1-b][1,3]thiazole-3,7-dicarboxylic acid is a chemical compound with a complex molecular structure. It contains a benzyl group, two methyl groups, and a tetrahydroimidazo[5,1-b][1,3]thiazole ring system with two carboxylic acid groups. 5-benzyl-2,2-dimethyl-2,3,7,7a-tetrahydroimidazo[5,1-b][1,3]thiazole-3,7-dicarboxylic acid is a heterocyclic molecule with potential pharmaceutical applications, particularly in the development of new drugs for various medical conditions. The presence of carboxylic acid groups suggests potential for binding to proteins or other biological targets, and the unique ring system may offer specific biological activity. Further research is needed to fully understand the properties and potential uses of this compound.

Upstream product

• 61-33-6 6-(2-phenylacetamido)penicillanic acid 
• 3264-88-8 benzylpenicillenic acid 
• 61-33-6 penicillin G 
• 13057-98-2 benzylpenicilloic acid 
• 22572-05-0 penicillamine hydrochloride 
• 1212-44-8 2-Benzyl-4-[1-methoxy-meth-(E)-ylidene]-4H-oxazol-5-one 
• 25526-04-9 L-(+)-penicillamine hydrochloride 
• 52-67-5 3,3-dimethyl-D-cysteine 

Downstream Products

• 501-34-8 benzylpenilloic acid 

Relevant articles and documents

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The Chemical Reactivity of Penicillins and Other β-Lactam Antibiotics

The rates of the acid catalysed hydrolysis of penicillins and cephalosporins are linear in Ho and, unlike other amides, show no rate maximum with increasing acidity.Electron-withdrawing substituents at C-6 in penicillins decrease the rate of hydrolysis with a ρI of ca. 4 and they decrease the rate when attached to the amine leaving group.The acylamido-group at C-6 in penicillins, but not at C-7 in cephalosporins, exhibits neighbouring group participation with a rate enhancement of ca. 103.The absence of penicillenic acid formation from benzylpenicillin in acidic solution is not due to the ionisation of the carboxy-group.These observations are rationalised by a scheme involving N-protonation and formation of an acylium ion intermediate.The alkaline hydrolysis of penicillins proceeds 102 faster than a β-lactam after correction for substituent effects.There is no evidence for substantial inhibition of amide resonance in the bicyclic β-lactam antibiotics, little evidence to indicate extra strain in these systems and no evidence that expulsion of the leaving group at C-3 in cephalosporins occurs in the transition state.