1309460-01-2

Basic information

• Product Name: 2-tosylethyl 3-hydroxy-2,2-bis(hydroxymethyl)propanoate
• Synonyms: 2-tosylethyl 3-hydroxy-2,2-bis(hydroxymethyl)propanoate
• CAS NO: 1309460-01-2
• Molecular Weight: 332.375
• Mol File: 1309460-01-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-tosylethyl 3-hydroxy-2,2-bis(hydroxymethyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-tosylethyl 3-hydroxy-2,2-bis(hydroxymethyl)propanoate(1309460-01-2)
• EPA Substance Registry System: 2-tosylethyl 3-hydroxy-2,2-bis(hydroxymethyl)propanoate(1309460-01-2)

Safety Data

• Hazardous Substances Data: 1309460-01-2(Hazardous Substances Data)

Upstream product

• 22381-54-0 2-(p-tolylsulfonyl)ethanol 
• 1309460-17-0 2-tosylethyl 3-(benzyloxy)-2,2-bis(benzyloxymethyl)propanoate 
• 1257583-44-0 3-(benzyloxy)-2,2-bis(benzyloxymethyl)propanoic anhydride 

Relevant articles and documents

Efficient and controllably selective preparation of esters using uronium-based coupling agents

Carboxylic acid esters can be prepared in excellent yields at room temperature from an acid and either a phenol or an aliphatic alcohol using the peptide coupling reagents, TBTU, TATU, or COMU, in the presence of organic bases. Reactions using TBTU and TATU are faster but do not occur with tertiary alcohols. Selectivity between reaction with primary or secondary alcohols in diols and polyols can be achieved with choice of base and coupling agent.