1309598-05-7

Basic information

• Product Name: 2-[4-bromo-5-(4-trifluoromethylphenyl)-thiophen-2-yl]-[1,3]dioxolane
• Synonyms: 2-[4-bromo-5-(4-trifluoromethylphenyl)-thiophen-2-yl]-[1,3]dioxolane
• CAS NO: 1309598-05-7
• Molecular Weight: 379.197
• Mol File: 1309598-05-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[4-bromo-5-(4-trifluoromethylphenyl)-thiophen-2-yl]-[1,3]dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-bromo-5-(4-trifluoromethylphenyl)-thiophen-2-yl]-[1,3]dioxolane(1309598-05-7)
• EPA Substance Registry System: 2-[4-bromo-5-(4-trifluoromethylphenyl)-thiophen-2-yl]-[1,3]dioxolane(1309598-05-7)

Safety Data

• Hazardous Substances Data: 1309598-05-7(Hazardous Substances Data)

Upstream product

• 58267-85-9 2-(4-bromo-thiophen-2-yl)-[1,3]dioxolane 
• 402-43-7 p-trifluoromethylphenyl bromide 

Relevant articles and documents

Palladium-catalyzed direct 5-arylation of formyl- or acetyl-halothiophene derivatives

Pd(OAc)2 was found to catalyze the direct arylation of some functionalized halothiophene derivatives allowing the synthesis in only one step of polyfunctionalized arylated thiophenes. In the presence of 2-acetyl-3-chlorothiophene, 2-acetyl-4-chlorothiophene, 2-acetyl-3- bromothiophene diethylacetal or 2-(4-bromothiophen-2-yl)-[1,3]dioxolane, and a variety of aryl bromides, the 5-arylation products were obtained in moderate to high yields employing only 0.5 mol% catalyst. On the other hand, the use of 2-formyl-3-chlorothiophene, 2-acetyl-3-bromothiophene or 2-formyl-3- bromothiophene gave disappointing results.