131035-57-9

Basic information

• Product Name: methyl 3-hydroxy-4-(2,2,2-trifluoroacetamido)benzoate
• Synonyms: methyl 3-hydroxy-4-(2,2,2-trifluoroacetamido)benzoate
• CAS NO: 131035-57-9
• Molecular Weight: 263.173
• Mol File: 131035-57-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 3-hydroxy-4-(2,2,2-trifluoroacetamido)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-hydroxy-4-(2,2,2-trifluoroacetamido)benzoate(131035-57-9)
• EPA Substance Registry System: methyl 3-hydroxy-4-(2,2,2-trifluoroacetamido)benzoate(131035-57-9)

Safety Data

• Hazardous Substances Data: 131035-57-9(Hazardous Substances Data)

Upstream product

• 20442-96-0 methyl 4-azidobenzoate 
• 76-05-1 trifluoroacetic acid 
• 619-45-4 4-methoxycarbonyl aniline 
• 713-52-0 methyl 3-hydroxy-4-nitrobenzoate 
• 63435-16-5 3-hydroxy-4-aminobenzoic acid methyl ester 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 131035-59-1 Methyl 2-amino-3-hydroxy-4-N-trifluoroacetylaminobenzoate 
• 131035-58-0 Methyl 3-hydroxy-2-nitro-4-N-trifluoroacetylaminobenzoate 

Relevant articles and documents

C-H oxygenation and N-trifluoroacylation of arylamines under metal-free conditions: A convenient approach to 2-aminophenols and N-trifluoroacyl-ortho- aminophenols

Direct ortho-hydroxylation through C-H oxygenation and N-trifluoroacylation of anilines was achieved in a single step under metal-free conditions by using a combination of TFA and oxone. The method allowed the formation of functionalised amino phenolic compounds such as ortho-hydroxy-N- trifluoroacetanilides in good yields with broad substrate scope.