1310369-79-9

Basic information

• Product Name: C₁₉H₂₀BrClN₂O₃S
• CAS NO: 1310369-79-9
• Molecular Weight: 471.802
• Mol File: 1310369-79-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₂₀BrClN₂O₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₂₀BrClN₂O₃S(1310369-79-9)
• EPA Substance Registry System: C₁₉H₂₀BrClN₂O₃S(1310369-79-9)

Safety Data

• Hazardous Substances Data: 1310369-79-9(Hazardous Substances Data)

Upstream product

• 1310369-66-4 C₁₃H₁₇ClN₂O 
• 2905-25-1 o-bromobenzenesulfonyl chloride 
• 1310369-55-1 C₁₅H₁₉ClN₂O₂ 
• 108761-32-6 1-acetyl-5-chloro-1H-indol-3-yl acetate 
• 21739-93-5 2-bromo-5-chlorobenzoic acid 
• 133433-34-8 5-chloro-2-<(carboxymethyl)amino>-benzoic acid 
• 62486-02-6 1-acetyl-5-chloro-1,2-dihydro-3H-indol-3-one 

Relevant articles and documents

Design, synthesis and pharmacological evaluation of conformationally restricted N-arylsulfonyl-3-aminoalkoxy indoles as a potential 5-HT6 receptor ligands

A series of novel conformationally restricted N1-arylsulfonyl-3-aminoalkoxy indoles were designed and synthesized as 5-HT6 receptor (5-HT6R) ligands. Many of the synthesized compounds have moderate in vitro-binding affinities at 5-HT6R. The lead compound 8b (% inhibition=97.2 at 1 μM) from this series has good pharmacokinetic profile in male Wister rats and is active in animal model of cognition like Morris water maze. The details of chemistry, SAR, pharmacokinetics and pharmacological data constitute the subject matter of this report.