1310554-96-1Relevant articles and documents
The myo-1,2-diaminocyclitol scaffold defines potent glucocerebrosidase activators and promising pharmacological chaperones for gaucher disease
Trapero, Ana,Llebaria, Amadeu
, p. 614 - 619 (2011/10/08)
A series of cyclitol derivatives with myo-configuration are β-glucocerebrosidase (GCase) inhibitors and show excellent characteristics for the development of pharmacological chaperones for enzyme deficiency in Gaucher disease (GD). The most potent inhibit